DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG32055 and RTN4RL1

DIOPT Version :9

Sequence 1:NP_729599.1 Gene:CG32055 / 39188 FlyBaseID:FBgn0052055 Length:534 Species:Drosophila melanogaster
Sequence 2:NP_848663.1 Gene:RTN4RL1 / 146760 HGNCID:21329 Length:441 Species:Homo sapiens


Alignment Length:270 Identity:79/270 - (29%)
Similarity:105/270 - (38%) Gaps:58/270 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   218 EELHLHSNWLEHLDMGIFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLELLDYSSN-IVKVL 281
            |.:.|.:|.:..|..|.|  .|.:..|.:.:||:..|..:.|..   ...||.||...| .::.|
Human    57 ERVFLQNNRIGLLQPGHF--SPAMVTLWIYSNNITYIHPSTFEG---FVHLEELDLGDNRQLRTL 116

  Fly   282 DDSVFCRLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDLS 346
            ....|..|.||..|.|:...::.:....|.||.|||.|:||.|.|..|.||:|.:|..|..|.|.
Human   117 APETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLH 181

  Fly   347 KNNIQKLGLRVFGERILRKLIYLDLSNNYIADLHPLALSSMPFIKELRLRRNRLVSLDLRMFAPL 411
            .|.:..||...|     |.|:.||                     .|.|..|:|..:..:.|..|
Human   182 GNKLWSLGPGTF-----RGLVNLD---------------------RLLLHENQLQWVHHKAFHDL 220

  Fly   412 RQLQLLTINENRLEEIDGEILDTLDRLNHLELNNNRLTFLPDLKSSQNLLQLRNITLEGNPWQCL 476
            |:|..|.:..|.|.|:.||.|..|..|..|.||                         ||||.|.
Human   221 RRLTTLFLFNNSLSELQGECLAPLGALEFLRLN-------------------------GNPWDCG 260

  Fly   477 C-LDEITSWL 485
            | ...:..||
Human   261 CRARSLWEWL 270

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32055NP_729599.1 leucine-rich repeat 76..99 CDD:275380
leucine-rich repeat 100..123 CDD:275380
LRR_8 128..180 CDD:290566
leucine-rich repeat 128..147 CDD:275380
leucine-rich repeat 148..171 CDD:275380
leucine-rich repeat 172..192 CDD:275380
LRR_RI <187..400 CDD:238064 54/182 (30%)
LRR_8 192..251 CDD:290566 9/32 (28%)
leucine-rich repeat 193..216 CDD:275380
leucine-rich repeat 217..240 CDD:275380 6/21 (29%)
leucine-rich repeat 241..267 CDD:275380 5/25 (20%)
leucine-rich repeat 268..291 CDD:275380 8/23 (35%)
LRR_8 290..350 CDD:290566 24/59 (41%)
leucine-rich repeat 292..315 CDD:275380 6/22 (27%)
leucine-rich repeat 316..339 CDD:275380 12/22 (55%)
LRR_8 340..400 CDD:290566 14/59 (24%)
leucine-rich repeat 340..365 CDD:275380 7/24 (29%)
leucine-rich repeat 366..389 CDD:275380 3/22 (14%)
leucine-rich repeat 390..413 CDD:275380 6/22 (27%)
LRR_8 391..448 CDD:290566 20/56 (36%)
leucine-rich repeat 414..437 CDD:275380 9/22 (41%)
RTN4RL1NP_848663.1 leucine-rich repeat 37..54 CDD:275380
LRR 1 55..76 6/20 (30%)
LRR_8 57..111 CDD:316378 16/58 (28%)
leucine-rich repeat 57..77 CDD:275380 6/21 (29%)
LRR 2 77..98 5/20 (25%)
leucine-rich repeat 78..101 CDD:275380 5/25 (20%)
LRR 3 101..123 7/21 (33%)
leucine-rich repeat 102..126 CDD:275380 8/23 (35%)
LRR_8 126..185 CDD:316378 24/58 (41%)
LRR 4 126..147 5/20 (25%)
leucine-rich repeat 127..150 CDD:275380 6/22 (27%)
LRR 5 150..171 12/20 (60%)
leucine-rich repeat 151..174 CDD:275380 12/22 (55%)
LRR_8 174..233 CDD:316378 21/84 (25%)
LRR 6 174..195 7/25 (28%)
leucine-rich repeat 175..198 CDD:275380 9/27 (33%)
LRR 7 198..219 7/41 (17%)
leucine-rich repeat 199..222 CDD:275380 8/43 (19%)
LRR 8 222..243 8/20 (40%)
leucine-rich repeat 223..246 CDD:275380 9/22 (41%)
TPKR_C2 255..300 CDD:326558 7/16 (44%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 304..382
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 397..417
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.