DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32055 and si:dkey-182i3.11

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	XP_021322095.1	Gene:	si:dkey-182i3.11 / 100334238	ZFINID:	ZDB-GENE-121214-258	Length:	710	Species:	Danio rerio

Alignment Length:	588	Identity:	157/588 - (26%)
Similarity:	240/588 - (40%)	Gaps:	124/588 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DLQECEDLGNGS---YLCRE------IESFEQL----------NRYVGKNWKSVK-VVNEHTGIE 63
            :|.|...|.||:   |..|.      .|:|.:|          |..:..||:||: :.:.|.|..
Zfish    73 NLLEFPPLPNGTKHFYATRNKIQALPNETFHELRVLDLTKNVFNLSLNTNWQSVRGLTHLHLGGN 137

  Fly    64 RAE---DGELPGLSTLLQLDLSE------------------------------SGGVTLGEKGLQ 95
            |..   ..:..||..|..||||.                              |.||..|...|.
Zfish   138 RLRALTPRQFEGLLNLQVLDLSNNAIKSLPQMFLYGLINLQTLNLNINQILSLSYGVLEGPLALT 202

  Fly    96 DFKA------------------LQKLNLTHAQLDELKSEQFPNPSEMINFDVSYNDILAITTKLM 142
            |.:.                  |.||.|:..:|..:.:..|...:.:.:.|:..|.:..|.|.::
Zfish   203 DLQLRDNMIDMIEMNVFENCTYLAKLYLSKNKLKSVGNGSFKGATGLNHLDLGLNGLAGIPTIVL 267

  Fly   143 SGFGNLVYANFSENLIAVIEPNAFRHMKNLRFLDLTTNYQENITLGENANLR---FLSISNNNLR 204
            ....||......:|.|..|..|.|..:.:|:.|||:.|...:|:.|...:|.   :|.:|.|.|:
Zfish   268 QETSNLTSLYLQKNDITSIPDNVFSEILSLKHLDLSYNGLVSISNGSFRSLSQLVYLDLSFNQLQ 332

  Fly   205 DFQWCHLRVLPKLEELHLHSNWLEHLDMGIFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLE 269
            .........|.|||.|:|:.|.|..|...:|..|..|:.|.:.:||:..|...||.....:..|:
Zfish   333 TLTQHVFEDLGKLENLNLYHNKLTSLPNNMFKNLTMLKELQLDSNNISVIPPDLFHPLSALKDLQ 397

  Fly   270 L---------------------LDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGL 313
            |                     ||.|||.:..:.:.:|  .|.|:.|||..|.|:.|...:|..|
Zfish   398 LDNNHISKLHSHTFKKLRQLKQLDISSNDLTKIPNHLF--HKNLKELNLENNHISFISKFSFKNL 460

  Fly   314 SSLQTLHLQGNKISILPDDVFANLTALEKLDLSKNNIQKLGLRVFGERILRKLIYLDLSNNYIAD 378
            ..||:|.|..|.:|.|..::..|||.|.:|.|::|.|:.:.:..|  :.|..|..||||||.:..
Zfish   461 HRLQSLKLSHNNLSKLYRELLTNLTRLRELLLNENQIETIPVGFF--KGLENLRVLDLSNNKMHF 523

  Fly   379 LHPLALSSMPFIKELRLRRNRLVSLDLRMFAPLRQLQLLTINENRLEEIDGEILDTLDRLNHLEL 443
            :.|.|.:.:..:|:|.|..|.|.:|...:||.||.|..|.:..|:|..:...:...|..|..|.|
Zfish   524 ILPDAFNDLSALKDLDLSFNFLHNLPEDIFASLRNLTKLHLQNNKLRYLPSRLFSALVGLEELHL 588

  Fly   444 NNNRLTFLP-------------DLKSSQ----------NLLQLRNITLEGNPWQC--LCLDEITS 483
            :.|.:..:.             |:||:|          .|.:|:.|.|:||||.|  :.:..|:.
Zfish   589 DRNYIQRIHPTQFEGLVKLHELDMKSNQLRSMEDGTLMPLRKLKRIHLDGNPWDCSTVVILYISQ 653

  Fly   484 WLN 486
            |.|
Zfish   654 WFN 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	11/52 (21%)
		leucine-rich repeat	100..123	CDD:275380	6/22 (27%)
		LRR_8	128..180	CDD:290566	15/51 (29%)
		leucine-rich repeat	128..147	CDD:275380	4/18 (22%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		leucine-rich repeat	172..192	CDD:275380	7/19 (37%)
		LRR_RI	<187..400	CDD:238064	72/236 (31%)
		LRR_8	192..251	CDD:290566	19/61 (31%)
		leucine-rich repeat	193..216	CDD:275380	6/25 (24%)
		leucine-rich repeat	217..240	CDD:275380	9/22 (41%)
		leucine-rich repeat	241..267	CDD:275380	7/25 (28%)
		leucine-rich repeat	268..291	CDD:275380	8/43 (19%)
		LRR_8	290..350	CDD:290566	24/59 (41%)
		leucine-rich repeat	292..315	CDD:275380	9/22 (41%)
		leucine-rich repeat	316..339	CDD:275380	9/22 (41%)
		LRR_8	340..400	CDD:290566	20/59 (34%)
		leucine-rich repeat	340..365	CDD:275380	7/24 (29%)
		leucine-rich repeat	366..389	CDD:275380	9/22 (41%)
		leucine-rich repeat	390..413	CDD:275380	9/22 (41%)
		LRR_8	391..448	CDD:290566	19/56 (34%)
		leucine-rich repeat	414..437	CDD:275380	5/22 (23%)
si:dkey-182i3.11	XP_021322095.1	PLN00113	97..>617	CDD:331614	137/523 (26%)
		leucine-rich repeat	129..152	CDD:275380	5/22 (23%)
		leucine-rich repeat	153..176	CDD:275380	5/22 (23%)
		leucine-rich repeat	177..200	CDD:275380	4/22 (18%)
		leucine-rich repeat	201..224	CDD:275380	2/22 (9%)
		leucine-rich repeat	225..248	CDD:275380	6/22 (27%)
		leucine-rich repeat	249..272	CDD:275380	4/22 (18%)
		leucine-rich repeat	273..296	CDD:275380	6/22 (27%)
		leucine-rich repeat	297..320	CDD:275380	8/22 (36%)
		leucine-rich repeat	321..344	CDD:275380	5/22 (23%)
		leucine-rich repeat	345..368	CDD:275380	9/22 (41%)
		leucine-rich repeat	369..392	CDD:275380	7/22 (32%)
		leucine-rich repeat	393..438	CDD:275380	8/46 (17%)
		leucine-rich repeat	417..436	CDD:275380	6/20 (30%)
		leucine-rich repeat	439..462	CDD:275380	9/22 (41%)
		leucine-rich repeat	463..486	CDD:275380	9/22 (41%)
		leucine-rich repeat	487..510	CDD:275380	7/24 (29%)
		leucine-rich repeat	511..534	CDD:275380	9/22 (41%)
		leucine-rich repeat	535..558	CDD:275380	9/22 (41%)
		leucine-rich repeat	559..582	CDD:275380	5/22 (23%)
		leucine-rich repeat	583..606	CDD:275380	4/22 (18%)
		leucine-rich repeat	607..628	CDD:275380	4/20 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D299282at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920