DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6628 and PI16

DIOPT Version :9

Sequence 1:	NP_648386.1	Gene:	CG6628 / 39183	FlyBaseID:	FBgn0036072	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	221	Identity:	56/221 - (25%)
Similarity:	83/221 - (37%)	Gaps:	48/221 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LVNLTG----LQD----LILGEHNALRNVLASGKIINLPKPDRMATLQWHSELADLATLNVKQCV 118
            ||..||    |.|    |::..||..|..::       |....|..::|..|||..|....:|||
Human    18 LVATTGPVGALTDEEKRLMVELHNLYRAQVS-------PTASDMLHMRWDEELAAFAKAYARQCV 75

  Fly   119 LQHDSCHNTPDFHNSGQNLALVNITLLPEDGNHTDECL-VKESIGGWWNQSINITKEQLQRFPKG 182
            ..|:.     :....|:||..:           |||.: |..::..|.::..:.........|
Human    76 WGHNK-----ERGRRGENLFAI-----------TDEGMDVPLAMEEWHHEREHYNLSAATCSP-- 122

  Fly   183 KLGDSIRNFAVMARDNNTHVGCAALRFEKPAG---HPLFLLACNY--ASNYVPDWPIYKE--KAI 240
              |....::..:.......:||.:...||..|   ..:.||.|||  ..|.....| |:|  ...
Human   123 --GQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRP-YQEGTPCS 184

  Fly   241 GCQSGSDLKYPSLCK---AGEEYQDL 263
            .|.||...| .|||:   :.|:.|||
Human   185 QCPSGYHCK-NSLCEPIGSPEDAQDL 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6628	NP_648386.1	SCP_euk	69..225	CDD:240180	36/165 (22%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	34/159 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920