DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6628 and vap-1

DIOPT Version :9

Sequence 1:	NP_648386.1	Gene:	CG6628 / 39183	FlyBaseID:	FBgn0036072	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001024553.1	Gene:	vap-1 / 181768	WormBaseID:	WBGene00006886	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	262	Identity:	58/262 - (22%)
Similarity:	95/262 - (36%)	Gaps:	59/262 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SQDNATAPPTDYCQSGLC------PSLKKHIACKNKGELGKQCSPDAHLVNLTGLQDLILGEHNA 78
            |....|......|::|||      |.::....|.:..:...|...:            .|..||.
Worm   193 SDAECTTYSDSQCKNGLCYKAPQAPVVETFTMCPSVTDQSDQARQN------------FLDTHNK 245

  Fly    79 LRNVLASGKIIN-------LPKPDRMATLQWHSELADLATLNVKQCVLQHDSCHNTPDFHNSGQN 136
            ||..||.|...:       .|...:|..|::...:...|....|.|:.||.:....|..   |:|
Worm   246 LRTSLAKGLEADGIAAGAFAPMAKQMPKLKYSCTVEANARTWAKGCLYQHSTSAQRPGL---GEN 307

  Fly   137 LALVNITLLPEDGNHTDECLVKESIGGWWNQ-------SINITKEQLQRFPKGKLGDSIRNFAVM 194
            |.:::|..:|:...      .::|...||::       |.||..:.:  |.:|     :.::..|
Worm   308 LYMISINNMPKIQT------AEDSSKAWWSELKDFGVGSDNILTQAV--FDRG-----VGHYTQM 359

  Fly   195 ARDNNTHVGCAALRFEKPAGHPLFLLA-CNY--ASNYVPDWPIYKEKAIGCQSGSDLKYPSLCKA 256
            |.:..|.:||..      ...|.|..: |.|  |.||: :..|| .|...|.:.:|......|..
Worm   360 AWEGTTEIGCFV------ENCPTFTYSVCQYGPAGNYM-NQLIY-TKGSPCTADADCPGTQTCSV 416

  Fly   257 GE 258
            .|
Worm   417 AE 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6628	NP_648386.1	SCP_euk	69..225	CDD:240180	39/172 (23%)
vap-1	NP_001024553.1	SCP	31..175	CDD:214553
vap-1	NP_001024553.1	SCP	234..386	CDD:214553	40/185 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020