DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6628 and vap-2

DIOPT Version :9

Sequence 1:	NP_648386.1	Gene:	CG6628 / 39183	FlyBaseID:	FBgn0036072	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	263	Identity:	68/263 - (25%)
Similarity:	101/263 - (38%)	Gaps:	75/263 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 PTDYC--QSGLC--PSLKKHIACKNKGELGKQCSPDAHLV-NLTGLQDLILGEHNALRNVLASGK 87
            |...|  ..|||  ||:.|    .:.|..  ||  |..|| ::|  ::..|.:||..|:.||.|.
Worm   280 PGSKCLVPEGLCQAPSMVK----DDGGSF--QC--DNSLVSDVT--RNFTLEQHNFYRSRLAKGF 334

  Fly    88 IIN------LPKPDRMATLQWHSELADLATLNVKQCVLQHDSCHNTPDFHNSGQNLALVNITLLP 146
            ..|      .||..:|..:::...|...|......||..|.:.:..|   |.||||.:.:.:
Worm   335 EWNGETNTSQPKASQMIKMEYDCMLERFAQNWANNCVFAHSAHYERP---NQGQNLYMSSFS--- 393

  Fly   147 EDGNHTDECLVKESIGGWWNQSINITKEQLQRFP--------------KGKLGDSIRNFAVMARD 197
               |.....|:..::..||        ::|:.|.              |||   :|.::..||.|
Worm   394 ---NPDPRSLIHTAVEKWW--------QELEEFGTPIDNVLTPELWDLKGK---AIGHYTQMAWD 444

  Fly   198 NNTHVGCAALRFEKPAGHPLFLLACNY--ASNYVPDWPIYKEKAIG--------CQSGSDL-KYP 251
            ....:||......|     :..:.|:|  |.|...: .||:   ||        |..|:|. |..
Worm   445 RTYRLGCGIANCPK-----MSYVVCHYGPAGNRKNN-KIYE---IGDPCEVDDDCPIGTDCEKTT 500

  Fly   252 SLC 254
            |||
Worm   501 SLC 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6628	NP_648386.1	SCP_euk	69..225	CDD:240180	40/177 (23%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	41/179 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920