DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6628 and crispld1a

DIOPT Version :9

Sequence 1:	NP_648386.1	Gene:	CG6628 / 39183	FlyBaseID:	FBgn0036072	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	XP_001920421.2	Gene:	crispld1a / 100149104	ZFINID:	ZDB-GENE-090612-1	Length:	508	Species:	Danio rerio

Alignment Length:	273	Identity:	56/273 - (20%)
Similarity:	90/273 - (32%)	Gaps:	69/273 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TELVVALMLF-----GFLQVAFSQDNATAPPTDYCQSGLCPSLKKHIACKNKGELGKQCSPDAHL 62
            |..|.|::||     |||...:.:|:|.....|            .:..:.:|:         ..
Zfish    18 TRTVFAMVLFNATDLGFLLEKYLEDDADDDAGD------------RVMERQRGK---------RA 61

  Fly    63 VNLTGLQDLILGEHNALRNVLASGKIINLPKPDRMATLQWHSELADLATLNVKQCVLQHDSCHNT 127
            :..:.:| .||..||.||     |::  .|....|..:.|.:||...|....:.|:.:|......
Zfish    62 ITASDMQ-AILDLHNKLR-----GQV--YPPASNMEYMVWDNELERSAEEWAETCLWEHGPAGLL 118

  Fly   128 PDFHNSGQNLALVNITLLPEDGNHTDECLVKES-IGGWWNQ----SINITKEQLQRFPKGKLGDS 187
            |..   ||||           |.|........| :..|:::    |....:|.....|....|..
Zfish   119 PQI---GQNL-----------GVHWGRYRPPTSHVQAWYDEVKDYSFPYPQECNPHCPFRCSGPV 169

  Fly   188 IRNFAVMARDNNTHVGCAA-----LRFEKPAGHPLFLLACNYAS-----NYVPDWPIYKEKAIGC 242
            ..::..:....::.:|||.     :............|.|||:.     .|.|    ||. ...|
Zfish   170 CTHYTQLVWATSSRIGCAINVCYNMNVWGQIWAKAVYLVCNYSPKGNWWGYAP----YKH-GTSC 229

  Fly   243 QSGSDLKYPSLCK 255
             |.....|..:|:
Zfish   230 -SACPPSYGGVCR 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6628	NP_648386.1	SCP_euk	69..225	CDD:240180	35/165 (21%)
crispld1a	XP_001920421.2	SCP_euk	68..212	CDD:240180	35/165 (21%)
		LCCL	298..381	CDD:128866
		LCCL	401..500	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585694
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850