DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8072 and CRISPLD1

DIOPT Version :9

Sequence 1:	NP_648384.1	Gene:	CG8072 / 39181	FlyBaseID:	FBgn0036070	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	NP_113649.1	Gene:	CRISPLD1 / 83690	HGNCID:	18206	Length:	500	Species:	Homo sapiens

Alignment Length:	247	Identity:	56/247 - (22%)
Similarity:	77/247 - (31%)	Gaps:	97/247 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GKRHIGCDNNMMFDESCLRFHGLVNMAYFREYLLGLHNGYRQEVASNLFVDLPPAQKMPELVWDN 96
            |||.| .||:|                   :.:|.|||..|.:|       .|.|..|..:.||.
Human    53 GKRAI-TDNDM-------------------QSILDLHNKLRSQV-------YPTASNMEYMTWDV 90

  Fly    97 YLSVVAEYHLKRCQMDLPDDSCVATDDFSEPHFNYAEDFYPRPVIRQS------NVREMTILAEQ 155
            .|...||...:.|..:....|.:                   |.|.|:      ..|..|...:.
Human    91 ELERSAESWAESCLWEHGPASLL-------------------PSIGQNLGAHWGRYRPPTFHVQS 136

  Fly   156 WLDELYDLDDIATYSAEGEIR----------------NIINDRSSYMGCAA---------GQDYD 195
            |.||:.|.    :|..|.|..                .::...|:.:|||.         ||
Human   137 WYDEVKDF----SYPYEHECNPYCPFRCSGPVCTHYTQVVWATSNRIGCAINLCHNMNIWGQ--- 194

  Fly   196 LWNIHFVLVCYYSSGPPVEGNLYEEGIFN----ATLCP---NGQSDEYPNLC 240
            :|.....|||.||.    :||.:....:.    .:.||   .|...|  |||
Human   195 IWPKAVYLVCNYSP----KGNWWGHAPYKHGRPCSACPPSFGGGCRE--NLC 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8072	NP_648384.1	SCP_euk	61..208	CDD:240180	38/177 (21%)
CRISPLD1	NP_113649.1	SCP_euk	63..207	CDD:240180	38/176 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..281
		LCCL	291..375	CDD:128866
		LCCL	392..483	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151151
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750