DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8072 and Clec18a

DIOPT Version :9

Sequence 1:	NP_648384.1	Gene:	CG8072 / 39181	FlyBaseID:	FBgn0036070	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	XP_030099497.1	Gene:	Clec18a / 353287	MGIID:	2672935	Length:	615	Species:	Mus musculus

Alignment Length:	247	Identity:	50/247 - (20%)
Similarity:	84/247 - (34%)	Gaps:	52/247 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ILFLRSILAIDFCDIKSCHGKRHIGCDNNMMF---DESCLRFHGLVNMAYFREYLLGLHNGYRQE 74
            :|.|.|:|.|.:.:::....|:    |..:..   .||.|              :|..||..|..
Mouse    94 LLLLLSLLGITWTEVQPPQPKQ----DPTLQALSRKESFL--------------ILTAHNRLRSR 140

  Fly    75 VASNLFVDLPPAQKMPELVWDNYLSVVAEYHLKRCQMDLPDDSCVATDDFSEPHFNYAEDFYPRP 139
            |.       |||..|..:.|...|:.:||.....|...:..:  :|:......|..:  :....|
Mouse   141 VH-------PPAANMQRMDWSESLAQLAEARAALCVTSVTPN--LASTPGHNSHVGW--NVQLMP 194

  Fly   140 VIRQSNVREMTILAEQWLDELYDLDDIATYSAEGEIRNIINDRSSYMGCAAGQDYDLWNIHFVLV 204
            :...|.|..:.:...:.|...:...:.|..:.......::...||.:||.....:.........|
Mouse   195 MGSASFVEVVNLWFAEGLQYRHGDAECAHNATCAHYTQLVWATSSQLGCGRQPCFVDQEAMEAFV 259

  Fly   205 CYYSSGPPVEGNL---------YEEGIFNATLCPNGQS------DEYPNLCK 241
            |.||.|    ||.         |::|.: .:||....|      |....||:
Mouse   260 CAYSPG----GNWDINGKTVAPYKKGTW-CSLCTARVSGCFKAWDHAGGLCE 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8072	NP_648384.1	SCP_euk	61..208	CDD:240180	27/146 (18%)
Clec18a	XP_030099497.1	CAP_euk	129..263	CDD:349399	28/158 (18%)
		EGF_Lam	315..360	CDD:214543
		CLECT	390..514	CDD:153057
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841150
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850