DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8072 and vap-1

DIOPT Version :9

Sequence 1:	NP_648384.1	Gene:	CG8072 / 39181	FlyBaseID:	FBgn0036070	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	NP_001024553.1	Gene:	vap-1 / 181768	WormBaseID:	WBGene00006886	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	242	Identity:	53/242 - (21%)
Similarity:	85/242 - (35%)	Gaps:	68/242 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 GCDNNMMFDESCLRFHGLVNMAYFREYLLGLHNGYRQEVASNLFVD----LPPAQKMPELVWDNY 97
            ||.|..:.|::             |:.....||..|:.:|..|..:    |...:.:.||.||
Worm    22 GCSNTKINDQA-------------RKMFYDAHNDARRSMAKGLEPNKCGLLSGGKNVYELNWD-- 71

  Fly    98 LSVVAEYHLKRCQMDLP----DDSCVATDDFSEPHF--NYAEDFYPRPVIRQSNVREMTILAEQW 156
                       |:|:..    .|.|.::....:|.:  |||.  |...:........|.:  ..|
Worm    72 -----------CEMEAKAQEWADGCPSSFQTFDPTWGQNYAT--YMGSIADPLPYASMAV--NGW 121

  Fly   157 LDE-----LYDLDDIATYSAEGEIRNIINDRSSYMGCAAGQDYDLWNIHFVLVCYYSS-GPPVEG 215
            ..|     |.|.|:..|.||.....|:.|.::|..|||    |.|......:.|.|:. |.....
Worm   122 WSEIRTVGLTDPDNKYTNSAMFRFANMANGKASAFGCA----YALCAGKLSINCIYNKIGYMTNA 182

  Fly   216 NLYEEG----------IFNATLCPNGQSDEYP--------NLCKTLT 244
            .:||:|          .::.:.|.||...:.|        .:|.::|
Worm   183 IIYEKGDACTSDAECTTYSDSQCKNGLCYKAPQAPVVETFTMCPSVT 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8072	NP_648384.1	SCP_euk	61..208	CDD:240180	38/161 (24%)
vap-1	NP_001024553.1	SCP	31..175	CDD:214553	39/177 (22%)
vap-1	NP_001024553.1	SCP	234..386	CDD:214553
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920