DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr10 and PAPLN

DIOPT Version :9

Sequence 1:NP_729591.1 Gene:dpr10 / 39180 FlyBaseID:FBgn0052057 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_001352835.1 Gene:PAPLN / 89932 HGNCID:19262 Length:1278 Species:Homo sapiens


Alignment Length:401 Identity:89/401 - (22%)
Similarity:134/401 - (33%) Gaps:118/401 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 APPSHYPHGHKWNEPYFDLTM----PRNITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVG 99
            |||.|        ...:.:::    |..:.:.:|:...|.|..........||  .:|       
Human   899 APPFH--------SSSYRISLAGVEPSLVQAALGQLVRLSCSDDTAPESQAAW--QKD------- 946

  Fly   100 TYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPVR-SYSVNLNIVD-----LID 158
                  .|...:..||...:.:|.|...|..|||.|.|. ||:|.| |..:.|.|:.     |.:
Human   947 ------GQPISSDRHRLQFDGSLIIHPLQAEDAGTYSCG-STRPGRDSQKIQLRIIGGDMAVLSE 1004

  Fly   159 AETSDIMQQYYNDDAFYIAENRVYQSSNDEF--AGMFGPIQTVAVPTATILGGPDLYVDK----- 216
            ||.|...|.  .|.|             .:|  ||..||:.  |:|::.......|.:|:     
Human  1005 AELSRFPQP--RDPA-------------QDFGQAGAAGPLG--AIPSSHPQPANRLRLDQNQPRV 1052

  Fly   217 -----GSTINLTCIIKFSPEPPTHIFWYHQDKVLS----EETSGGRLKFKTIKSEETKSILLIYD 272
                 |..|.:||  :....||..|.|....:.:|    :....|.|....:..|:         
Human  1053 VDASPGQRIRMTC--RAEGFPPPAIEWQRDGQPVSSPRHQLQPDGSLVISRVAVED--------- 1106

  Fly   273 ADLLHSGKYSCYPSNTEIAS---IRVHVLQGERPEAMQTNAAPAAVA--------LAC------- 319
                 .|.|:|...|.:...   :::.|| ||    :..:..|..|.        |.|       
Human  1107 -----GGFYTCVAFNGQDRDQRWVQLRVL-GE----LTISGLPPTVTVPEGDTARLLCVVAGESV 1161

  Fly   320 ---WSCHFGQATQA--VRVISTMVAALVLLEACSSLLLQSGGGGGCPG-GGSPAGGMPTRVREIR 378
               ||.: |...||  .||..:....|::.    :|..:..|...|.. .||.|....|.|:.:.
Human  1162 NIRWSRN-GLPVQADGHRVHQSPDGTLLIY----NLRARDEGSYTCSAYQGSQAVSRSTEVKVVS 1221

  Fly   379 EKPLTNSLLDP 389
            ..| |....||
Human  1222 PAP-TAQPRDP 1231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr10NP_729591.1 Ig 63..143 CDD:299845 19/79 (24%)
IG_like 210..297 CDD:214653 18/103 (17%)
IGc2 217..287 CDD:197706 15/73 (21%)
PAPLNNP_001352835.1 TSP1 29..80 CDD:214559
ADAM_spacer1 183..298 CDD:310520
TSP1 308..361 CDD:214559
TSP1 369..424 CDD:214559
TSP1 424..481 CDD:214559
TSP1 488..539 CDD:214559
Kunitz_BPTI 753..805 CDD:278443
Papilin_u7 814..905 CDD:318767 4/13 (31%)
Ig 914..>978 CDD:325142 17/78 (22%)
I-set 1049..1119 CDD:254352 16/85 (19%)
IG 1139..1219 CDD:214652 20/84 (24%)
PLAC 1235..1267 CDD:312271
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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