DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and DIP-epsilon

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	73/285 - (25%)
Similarity:	102/285 - (35%)	Gaps:	75/285 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 CLTGLAVCYQRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAYLGC 75
            ||...:|.....:.|..|..|......:...|..|.       :.|:.  .|||...|::..|.|
  Fly    18 CLIASSVALSTDTGSEGNAGNVGGSTLNNVISEDPE-------FTDVI--ENITVPAGRNVKLAC 73

  Fly    76 RVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSY-----HRDIDEWTLQIKWAQQRDAGVY 135
            .||:||:..|||:......||||..:..|.:.|...::     ||   .|.|.|...|:.|.|.|
  Fly    74 SVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHR---TWFLHINNVQEEDRGRY 135

  Fly   136 ECQISTQPVRSYSVNLNIVDLIDAETSDIMQQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQTVA 200
            .|||:|               :.|:|                              .:|.::.|.
  Fly   136 MCQINT---------------VTAKT------------------------------QYGFVKVVV 155

  Fly   201 VPTA-TILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQD--KVLSEETSGGRLKFKTIKSE 262
            .|.. ..|...|:.|.:|..:.|.|..|.||||.  |.|...|  |::..:|       ..:...
  Fly   156 PPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPT--IKWKRDDGNKIVINKT-------LEVHDL 211

  Fly   263 ETKSILLIYDADLLHSGKYSCYPSN 287
            ||.| |.:.....||.|.|.|..||
  Fly   212 ETDS-LELERISRLHMGAYLCIASN 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	31/84 (37%)
		IG_like	210..297	CDD:214653	26/80 (33%)
		IGc2	217..287	CDD:197706	22/71 (31%)
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	35/143 (24%)
		Ig	69..139	CDD:143165	25/72 (35%)
		IG_like	165..249	CDD:214653	26/81 (32%)
		IGc2	172..237	CDD:197706	24/74 (32%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810