DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and lrit3a

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001122166.1	Gene:	lrit3a / 558559	ZFINID:	ZDB-GENE-080723-63	Length:	636	Species:	Danio rerio

Alignment Length:	206	Identity:	41/206 - (19%)
Similarity:	67/206 - (32%)	Gaps:	56/206 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 IQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIK 260
            ::...:.:||.:..|     .||.:.|.|.....|.|.  :.|         .|:.|.:...|:.
Zfish   250 VKPTVMTSATKITSP-----LGSNVLLRCDANGFPTPT--LLW---------TTADGSVVNNTVV 298

  Fly   261 SEETK-----SILLIYDADLLHSGKYSCYPSNT-----EIASIRVHVLQ----------GERPEA 305
            .|...     |||.::......:|.|.|...|.     ...::.|..:|          .::||.
Zfish   299 QESPGEGVRWSILSLHSIVFKDAGDYRCKAKNVAGNAEAYITLSVDGVQPTTPFPPINITKQPED 363

  Fly   306 MQTNA-APAAVALACWSCHFGQATQAVRVISTMVAALVLLEACSSLLLQSGGGGGCPGGG----S 365
            ..|.. .|..:.|   .......|...|.:.|.:..|...::            ..||||    .
Zfish   364 QPTTTFTPTKMPL---FTSLSPITITTRPVMTTMPPLTTRKS------------PIPGGGVQRSP 413

  Fly   366 PAGGMPTRVRE 376
            |||..|.:|::
Zfish   414 PAGDKPAKVQQ 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845
		IG_like	210..297	CDD:214653	20/96 (21%)
		IGc2	217..287	CDD:197706	17/74 (23%)
lrit3a	NP_001122166.1	LRR_8	81..141	CDD:290566
		leucine-rich repeat	83..106	CDD:275378
		LRR_4	107..145	CDD:289563
		leucine-rich repeat	107..130	CDD:275378
		LRR_8	129..>171	CDD:290566
		LRR_4	129..170	CDD:289563
		leucine-rich repeat	131..154	CDD:275378
		leucine-rich repeat	155..168	CDD:275378
		TPKR_C2	199..249	CDD:301599
		Ig	252..343	CDD:299845	21/106 (20%)
		IG_like	261..343	CDD:214653	19/97 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900