DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr10 and lrit1a

DIOPT Version :9

Sequence 1:NP_729591.1 Gene:dpr10 / 39180 FlyBaseID:FBgn0052057 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_001018174.2 Gene:lrit1a / 553943 ZFINID:ZDB-GENE-040924-5 Length:643 Species:Danio rerio


Alignment Length:376 Identity:68/376 - (18%)
Similarity:127/376 - (33%) Gaps:97/376 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 CYQRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAYLGCRVKHLGN 82
            |...:|:|....::||.:....|..|              |....:.|.||.:..|.|....:..
Zfish   230 CADPESLSGVLFSDAELRRCQGPRVH--------------TAVARVRSAVGNNVLLRCGTVGVPI 280

  Fly    83 KTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWT-LQIKWAQQRDAGVYECQI-----ST 141
            ..:|| |..|...|. ||......        ::...|: |.:.....||.|.|.|:.     |.
Zfish   281 PELAW-RRADGKPLN-GTVLLENS--------KEGIVWSILSVPAVSYRDTGKYICKATNYAGSA 335

  Fly   142 QPVRSYSVNLNIVDLIDA-----------------ETSDIMQQYYNDD--AFYIA---ENRVYQS 184
            :.|.|..:|       ||                 :.:.:::..|.:.  |.|::   :|.:..|
Zfish   336 EAVISLIIN-------DAPKMENPTLDPKPKLKSKKPNTMVKAAYQEKHIATYVSPTPKNGLPLS 393

  Fly   185 SNDEFAGMFGPIQTVAVPTA---TILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLS 246
            ....:.|.:..:::.....:   |....||.:::...: ||........:.|..:  ....||:.
Zfish   394 GTVSYTGPYPGMESDNAANSRMNTQTASPDGFLETNLS-NLAANTSSLQQDPDRV--VRSVKVIG 455

  Fly   247 EETSGGRLKFKTIKSEETKSILLIY----DADLLHSGKYSCYPSNTEIASIRVHVLQGERPEAMQ 307
            :......|.::...::.|.:..::|    :.|:   .:.:..|.|..|      |::|..|:...
Zfish   456 DTDYTVCLNWRAPTAKNTTAFSVLYAVFGERDM---RRINVSPGNNRI------VIEGLVPKTKY 511

  Fly   308 TNAAPAAVALACWSCHFGQATQAVRVISTMVAA-----------LVLLEAC 347
                   :|..|......:..|.| :.||..||           :|:..||
Zfish   512 -------IACVCVKGLIPKKEQCV-IFSTDAAASANGTQKLINVVVITVAC 554

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr10NP_729591.1 Ig 63..143 CDD:299845 20/85 (24%)
IG_like 210..297 CDD:214653 14/90 (16%)
IGc2 217..287 CDD:197706 10/73 (14%)
lrit1aNP_001018174.2 leucine-rich repeat 61..84 CDD:275378
LRR_8 63..119 CDD:290566
LRR_RI <77..175 CDD:238064
leucine-rich repeat 85..108 CDD:275378
LRR_8 108..167 CDD:290566
leucine-rich repeat 109..132 CDD:275378
leucine-rich repeat 133..156 CDD:275378
leucine-rich repeat 157..170 CDD:275378
LRRCT 199..243 CDD:214507 3/12 (25%)
I-set 252..343 CDD:254352 25/114 (22%)
Ig 259..333 CDD:299845 19/83 (23%)
fn3 448..515 CDD:278470 13/82 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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