DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and igsf9b

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_686205.6	Gene:	igsf9b / 553348	ZFINID:	ZDB-GENE-060810-28	Length:	2021	Species:	Danio rerio

Alignment Length:	395	Identity:	82/395 - (20%)
Similarity:	128/395 - (32%)	Gaps:	138/395 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 VGKSAYLGCRVK--------------HLGNKTVAWIR--HRDLHILTVGTYTYTTDQRF--QTSY 113
            ||..|.|||.:.              |:    |.|:|  :....::..|:||......:  :.|.
Zfish    34 VGGFAELGCSLTPPSEGATTPNLFPLHV----VEWVRLGYNVPILIKFGSYTPRVHPNYKGRVSL 94

  Fly   114 HRD----IDEWTLQIKWAQQRDAGVYECQISTQPVRSYSVNLNIVDLIDAETSDIMQQYYNDDAF 174
            .|.    :::.||:       |.|.:||:|.               |:| .|||
Zfish    95 SRGASLMVEKLTLE-------DEGWFECRIL---------------LLD-RTSD----------- 125

  Fly   175 YIAENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFW- 238
                  .:|:....|..:..|...:..|.      |.|.|..|.::.|.|....:|:|.  |.|
Zfish   126 ------EFQNGTWNFLSITAPPVFIKTPP------PFLEVLLGESLTLHCDAHGNPKPT--IIWR 176

  Fly   239 --------YHQDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLHSGKYSCYPSNTEIASIRV 295
                    ..:.:||:|..|..::..:|                   :|.|.|:.||:|......
Zfish   177 KYLSAAEKQEEIQVLNETLSLSKVTRET-------------------AGIYKCHVSNSEGNLTHS 222

  Fly   296 HVLQGERPEAM-------------------QTNAAPAAVALACWSCHFGQATQAVRVISTMVAAL 341
            ..||.:.|..:                   |..|.|:.:....|.  .||....:.::.:.|..|
Zfish   223 TQLQVKGPPIIIIAPEDTTMNMSQDAVLQCQAEAYPSNLTYEWWK--QGQNVYHIEILKSRVKIL 285

  Fly   342 V---LLEACSSLLLQSGGGGGC-PGGG---SPAGGM------PTRVREIREKPLTNSLLDPKIPS 393
            |   ||  .|:|:....|...| |..|   .||...      |.||..:..:......:..|||.
Zfish   286 VDGTLL--ISALIPDDSGNYTCRPTNGLMTPPAASAYLTVKHPARVVRMPRETYLPMGMGGKIPC 348

  Fly   394 TTSAE 398
            ...||
Zfish   349 PVQAE 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	22/97 (23%)
		IG_like	210..297	CDD:214653	21/95 (22%)
		IGc2	217..287	CDD:197706	15/78 (19%)
igsf9b	XP_686205.6	Ig	27..132	CDD:299845	28/141 (20%)
		IG_like	148..227	CDD:214653	22/105 (21%)
		IGc2	156..217	CDD:197706	17/81 (21%)
		Ig	237..323	CDD:299845	19/89 (21%)
		IG_like	237..323	CDD:214653	19/89 (21%)
		Ig	345..411	CDD:143165	5/9 (56%)
		IG_like	435..507	CDD:214653
		IGc2	437..496	CDD:197706
		FN3	512..603	CDD:238020
		FN3	621..709	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910