DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr10 and NTM

DIOPT Version :9

Sequence 1:NP_729591.1 Gene:dpr10 / 39180 FlyBaseID:FBgn0052057 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens


Alignment Length:327 Identity:76/327 - (23%)
Similarity:118/327 - (36%) Gaps:87/327 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 DLTMPR---NITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRF------QT 111
            |.|.|:   |:|...|:||.|.|.:.:...: |||:....  ||..|...:..|.|.      ||
Human    35 DATFPKAMDNVTVRQGESATLRCTIDNRVTR-VAWLNRST--ILYAGNDKWCLDPRVVLLSNTQT 96

  Fly   112 SYHRDIDEWTLQIKWAQQRDAGVYECQIST--QPVRS-----YSVNLNIVDLIDAETSDIMQQYY 169
            .|       :::|:.....|.|.|.|.:.|  .|..|     ..|:..||::    :|||.....
Human    97 QY-------SIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEI----SSDISINEG 150

  Fly   170 NDDAF---------------YIAENRVYQSSNDEFAGMFG------------PIQTVAVPT---- 203
            |:.:.               :|:...|...|.||:..:.|            ....||.|.    
Human   151 NNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRV 215

  Fly   204 -ATILGGPDLYVDKGSTI------NLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKS 261
             .|:...|.:...||:.:      .|.|  :.|..|.....||..||.|.|...|.:::.:...|
Human   216 KVTVNYPPYISEAKGTGVPVGQKGTLQC--EASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLS 278

  Fly   262 EETKSILLIYDADLLHSGKYSCYPSNT---EIASIRVH---------VLQGERPEAMQTNAAPAA 314
            :     |:.::......|.|:|..||.   ..|||.:.         :||..:..|:.....|.|
Human   279 K-----LIFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQEVKTTALTPWKGPGA 338

  Fly   315 VA 316
            |:
Human   339 VS 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr10NP_729591.1 Ig 63..143 CDD:299845 23/87 (26%)
IG_like 210..297 CDD:214653 24/104 (23%)
IGc2 217..287 CDD:197706 17/75 (23%)
NTMNP_001338930.1 Ig 44..132 CDD:416386 26/97 (27%)
Ig strand A' 44..49 CDD:409353 2/4 (50%)
Ig strand B 51..59 CDD:409353 4/7 (57%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 3/6 (50%)
Ig strand C 64..70 CDD:409353 3/6 (50%)
CDR2 71..83 CDD:409353 3/13 (23%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 10/40 (25%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 1/12 (8%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 2/8 (25%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 136..205 CDD:404760 12/72 (17%)
Ig strand A' 142..147 CDD:409353 3/4 (75%)
Ig strand B 153..160 CDD:409353 0/6 (0%)
Ig strand C 166..171 CDD:409353 0/4 (0%)
Ig strand D 177..180 CDD:409353 1/2 (50%)
Ig strand E 184..190 CDD:409353 1/5 (20%)
Ig strand F 197..204 CDD:409353 0/6 (0%)
Ig strand G 211..219 CDD:409353 0/7 (0%)
Ig_3 222..299 CDD:404760 19/83 (23%)
putative Ig strand A 223..229 CDD:409353 1/5 (20%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 2/8 (25%)
Ig strand F 292..297 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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