DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and DIP-gamma

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	64/285 - (22%)
Similarity:	106/285 - (37%)	Gaps:	66/285 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LWTALFCCLTGLAVCYQRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVG 68
            |.:.||..|.....|....:.:.::.::::..|               :|.| :....|:|...|
  Fly     5 LQSTLFVILIMATKCGSGSTQNQHHESSSQLDP---------------DPEF-IGFINNVTYPAG 53

  Fly    69 KSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDAG 133
            :.|.|.|.|::||...|.|:|..|..:|.:.....|.:.|... .|:|:..|.|:|...::.|.|
  Fly    54 REAILACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARISV-MHQDMHTWKLKISKLRESDRG 117

  Fly   134 VYECQISTQPVRSYSVNLNIVDLIDAET-SDIMQQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQ 197
            .|.|||:|.|::..      |..||.:. .||:                    |:|
  Fly   118 CYMCQINTSPMKKQ------VGCIDVQVPPDII--------------------NEE--------- 147

  Fly   198 TVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSE 262
                      ...||.|.:|....|||....:|:|  .:.|..:|..:......|..:...::|.
  Fly   148 ----------SSADLAVQEGEDATLTCKATGNPQP--RVTWRREDGEMILIRKPGSRELMKVESY 200

  Fly   263 ETKSILLIYDADLLHSGKYSCYPSN 287
            ...|:.|: ..:....|.|.|..||
  Fly   201 NGSSLRLL-RLERRQMGAYLCIASN 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	27/79 (34%)
		IG_like	210..297	CDD:214653	20/78 (26%)
		IGc2	217..287	CDD:197706	15/69 (22%)
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	32/98 (33%)
		Ig	47..129	CDD:299845	29/82 (35%)
		Ig	140..238	CDD:299845	24/127 (19%)
		IG_like	247..355	CDD:214653
		Ig	256..351	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	41	1.000	Domainoid score	I12439
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810