DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and klg

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	76/330 - (23%)
Similarity:	106/330 - (32%)	Gaps:	128/330 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GLAVCYQRQSVSNNNHNN-----------AEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLV 67
            |.||   ..::||...|:           |.:..|...|.....||.:.             ::|
  Fly    66 GFAV---EAAISNRGSNSRSMSNVQQSAVAASTLTATLPRFLSRGHTYR-------------AVV 114

  Fly    68 GKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDA 132
            |.:..|.|:|::|||..:.|  .|..::||......|.|:|.     |.||.:.|:|...:.:||
  Fly   115 GDTLVLPCQVENLGNFVLLW--RRGTNVLTASNIMVTRDERV-----RLIDGYNLEISDLEPQDA 172

  Fly   133 GVYECQISTQPVRSYSVNLNIVDLIDAETSDIMQQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQ 197
            |.|.||||.:                          .|.|..:..|..|             |..
  Fly   173 GDYVCQISDK--------------------------INRDQVHTVEILV-------------PPS 198

  Fly   198 TVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSE 262
            ..|:||:     ..|...||..|.|.|  |.|..|...|:|                   |.||.
  Fly   199 VRAIPTS-----GQLQARKGGPITLEC--KGSGNPVPSIYW-------------------TKKSG 237

  Fly   263 ETKSILLIYDADLL--------HSGKYSC-------------------YPSNTEIASIRVHVLQG 300
            ..||...|.|..:|        .:|.|.|                   ||.:.::....:|  .|
  Fly   238 ANKSTARIGDGPILTLEKLERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIH--SG 300

  Fly   301 ERPEA 305
            |..||
  Fly   301 EGFEA 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	28/79 (35%)
		IG_like	210..297	CDD:214653	24/113 (21%)
		IGc2	217..287	CDD:197706	22/96 (23%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	15/73 (21%)
		IG_like	109..195	CDD:214653	31/131 (24%)
		Ig	118..191	CDD:143165	28/105 (27%)
		IG_like	205..274	CDD:214653	22/94 (23%)
		IGc2	213..273	CDD:197706	20/80 (25%)
		IGc2	301..367	CDD:197706	3/5 (60%)
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810