DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr10 and Lac

DIOPT Version :9

Sequence 1:NP_729591.1 Gene:dpr10 / 39180 FlyBaseID:FBgn0052057 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:337 Identity:68/337 - (20%)
Similarity:103/337 - (30%) Gaps:104/337 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 VGKSAYLGCRVKHLGNKTVAWIR-HRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQR 130
            :|.:....|.|::.....|.::: ..|...|:.|:.....|.||...|..:...:.||||..|:.
  Fly    42 IGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQET 106

  Fly   131 DAGVYECQISTQPVRSYSVNLNI-------------VDLIDAETSDIMQQYY------------- 169
            |||.|.||:....|...|..:.:             ..::.:|.|::..:.|             
  Fly   107 DAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRR 171

  Fly   170 -------NDDAFYIAENRVYQSSNDEFAGM----------------------FGPIQTVAVPTAT 205
                   .|.|.|:......:|...|..|.                      |.|:.||..|.. 
  Fly   172 ENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRL- 235

  Fly   206 ILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEETKSILLI 270
               |..|..|    ::|.|.|:  ..||..|.|...|..|:.........|.| ..|.|.|.|.:
  Fly   236 ---GQALQYD----MDLECHIE--AYPPPAIVWTKDDIQLANNQHYSISHFAT-ADEYTDSTLRV 290

  Fly   271 YDADLLHSGKYSCYPSNTEIASIRVHVLQGERPEAMQTNAAPAAVALACWSCHFGQATQAVRVIS 335
            ...:....|.|.|..:|                                   .||:|...|.:..
  Fly   291 ITVEKRQYGDYVCKATN-----------------------------------RFGEAEARVNLFE 320

  Fly   336 TMVAALVLLEAC 347
            |::.  |...||
  Fly   321 TIIP--VCPPAC 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr10NP_729591.1 Ig 63..143 CDD:299845 22/76 (29%)
IG_like 210..297 CDD:214653 21/86 (24%)
IGc2 217..287 CDD:197706 18/69 (26%)
LacNP_523713.2 IG_like 36..131 CDD:214653 24/88 (27%)
FR1 37..50 CDD:409353 1/7 (14%)
Ig strand A' 37..42 CDD:409353 68/337 (20%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 13/30 (43%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 9/73 (12%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 0/4 (0%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 29/136 (21%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.