DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr10 and Opcml

DIOPT Version :9

Sequence 1:NP_729591.1 Gene:dpr10 / 39180 FlyBaseID:FBgn0052057 Length:408 Species:Drosophila melanogaster
Sequence 2:XP_006510497.1 Gene:Opcml / 330908 MGIID:97397 Length:354 Species:Mus musculus


Alignment Length:257 Identity:59/257 - (22%)
Similarity:87/257 - (33%) Gaps:86/257 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 DLTMPR---NITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRF------QT 111
            |.|.|:   |:|...|:||.|.|.:.....: |||:....  ||..|...::.|.|.      .|
Mouse    35 DATFPKAMDNVTVRQGESATLRCTIDDRVTR-VAWLNRST--ILYAGNDKWSIDPRVIILVNTPT 96

  Fly   112 SYHRDIDEWTLQIKWAQQRDAGVYECQIST--QPVRSYSVNLNIVDLIDAETSDIMQQYYNDDAF 174
            .|       ::.|:.....|.|.|.|.:.|  .|..|.      |.||                 
Mouse    97 QY-------SIMIQNVDVYDEGPYTCSVQTDNHPKTSR------VHLI----------------- 131

  Fly   175 YIAENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWY 239
                                    |.||...:....|:.|::||::.|.|:....|||.  :.|.
Mouse   132 ------------------------VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPT--VTWR 170

  Fly   240 HQDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLHSGKYSCYPSN----TEIASIRVHV 297
            |    ||.:...|      ..||:  ..|.|.|.....||:|.|...|    .::..:::.|
Mouse   171 H----LSVKEGQG------FVSED--EYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 220

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr10NP_729591.1 Ig 63..143 CDD:299845 22/87 (25%)
IG_like 210..297 CDD:214653 24/90 (27%)
IGc2 217..287 CDD:197706 21/69 (30%)
OpcmlXP_006510497.1 Ig 44..132 CDD:416386 28/144 (19%)
Ig strand A' 44..49 CDD:409353 2/4 (50%)
Ig strand B 51..59 CDD:409353 4/7 (57%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 3/6 (50%)
Ig strand C 64..70 CDD:409353 3/6 (50%)
CDR2 71..83 CDD:409353 3/13 (23%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 9/40 (23%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 1/12 (8%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 5/55 (9%)
FR4 125..132 CDD:409353 4/53 (8%)
Ig_3 135..206 CDD:404760 24/84 (29%)
Ig strand A 135..138 CDD:409353 1/2 (50%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand C 165..170 CDD:409353 1/6 (17%)
Ig strand C' 171..174 CDD:409353 2/6 (33%)
Ig strand F 198..206 CDD:409353 3/7 (43%)
Ig_3 223..300 CDD:404760
putative Ig strand A 224..230 CDD:409353
Ig strand B 240..244 CDD:409353
Ig strand C 253..257 CDD:409353
Ig strand E 279..283 CDD:409353
Ig strand F 293..298 CDD:409353
Ig strand G 306..309 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.