DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr10 and Dscaml1

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001101611.1	Gene:	Dscaml1 / 315615	RGDID:	1304887	Length:	2111	Species:	Rattus norvegicus

Alignment Length:	278	Identity:	62/278 - (22%)
Similarity:	104/278 - (37%)	Gaps:	89/278 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GLAVCYQRQSVSNNNHNNAEAK-PTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAYLGCRV 77
            |:..|..|.||.:..:   :|: ....|||              :...||||::.|:...:.|||
  Rat   539 GVYRCTARNSVGSAEY---QARINVRGPPS--------------IRAMRNITAVAGRDTLINCRV 586

  Fly    78 KHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDI--DEWTLQIKWAQQ-RDAGVYECQI 139
            ......::.|  ::|..:|              ...||.:  :..||::...|: .|.|.|.|.:
  Rat   587 IGYPYYSIKW--YKDALLL--------------PDNHRQVVFENGTLKLTDVQKGMDEGEYLCSV 635

  Fly   140 STQPVRSYSVNLNIVDLIDAETSDIMQQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQTVAVPTA 204
            ..||..|.|.::::.    .:...::|.:                   ||            |.|
  Rat   636 LIQPQLSISQSVHVA----VKVPPLIQPF-------------------EF------------PPA 665

  Fly   205 TILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEETKSILL 269
            :|          |..:.:.|::. |.:.|..|.|....:|:   .||..:   ||:|:|..|.|.
  Rat   666 SI----------GQLLYIPCVVS-SGDMPIRITWRKDGQVI---ISGSGV---TIESKEFMSSLQ 713

  Fly   270 IYDADLLHSGKYSCYPSN 287
            |....|.|:|.|:|..||
  Rat   714 ISSVSLKHNGNYTCIASN 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	18/82 (22%)
		IG_like	210..297	CDD:214653	23/78 (29%)
		IGc2	217..287	CDD:197706	21/69 (30%)
Dscaml1	NP_001101611.1	IG	101..173	CDD:214652
		IGc2	101..168	CDD:197706
		Ig	183..276	CDD:299845
		IG_like	195..276	CDD:214653
		I-set	291..369	CDD:254352
		IGc2	298..359	CDD:197706
		IGc2	386..447	CDD:197706
		I-set	466..560	CDD:254352	6/23 (26%)
		Ig	466..556	CDD:299845	5/19 (26%)
		IGc2	577..635	CDD:197706	16/73 (22%)
		IG_like	665..744	CDD:214653	25/84 (30%)
		Ig	673..739	CDD:143165	22/66 (33%)
		I-set	748..843	CDD:254352
		Ig7_DSCAM	765..843	CDD:143211
		I-set	849..942	CDD:254352
		Ig	861..949	CDD:299845
		FN3	945..1039	CDD:238020
		FN3	1046..1143	CDD:238020
		fn3	1151..1237	CDD:278470
		FN3	1249..1340	CDD:238020
		IGc2	1364..1428	CDD:197706
		FN3	1442..1532	CDD:238020
		FN3	1546..1618	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810