DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	67/287 - (23%)
Similarity:	94/287 - (32%)	Gaps:	92/287 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 PYFDLTMPRNITSLVGKSAYLGCRVK-HLGNKTVAWIRHRDLHILTVGTYTYTTDQR--FQTSYH 114
            |.|.::.|.|||..:.:.|.|.||.: :.||.|..|               |..|:.  ||....
  Rat   228 PPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTW---------------YWQDENVYFQNDLK 277

  Fly   115 ---RDIDEWTLQIKWAQQRDAGVYECQISTQPVRSYSVNLNIVDLIDAETSDIMQQYYNDDAFYI 176
               |.:.:.||.|...:..|||.|.|..|....||.|.:..:
  Rat   278 LRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYL----------------------- 319

  Fly   177 AENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQ 241
                                 ||..|...:...|.:||..|....:.|.:...| |.|.:.|...
  Rat   320 ---------------------TVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEP-PATVVKWNKD 362

  Fly   242 DKVLSEETSGG--RLKFKTIKSEETKSILLIYDADLLHSGKYSCYPSNT-----EIASIRV---- 295
            .:.|..|.:.|  .::..:|:.||.....|         |.|:|.|.||     :.|..|:
  Rat   363 GRPLQVEKNLGWTLMEDGSIRIEEATEEAL---------GTYTCVPYNTLGTMGQSAPARLVLKD 418

  Fly   296 ----HVLQG--ERPEAMQTNAAPAAVA 316
                .||.|  .|.||.:....|.|.|
  Rat   419 PPYFTVLPGWEYRQEAGRELLIPCAAA 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	24/85 (28%)
		IG_like	210..297	CDD:214653	24/101 (24%)
		IGc2	217..287	CDD:197706	17/71 (24%)
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273
		I-set	139..225	CDD:369462
		Ig	229..321	CDD:386229	30/150 (20%)
		Ig	<353..414	CDD:386229	17/69 (25%)
		Ig	438..502	CDD:319273	3/8 (38%)
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900