DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and Lsamp

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_030104997.1	Gene:	Lsamp / 268890	MGIID:	1261760	Length:	392	Species:	Mus musculus

Alignment Length:	278	Identity:	66/278 - (23%)
Similarity:	95/278 - (34%)	Gaps:	97/278 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 WNEPYFD-----LTMP---------------------------RNITSLVGKSAYLGCRVKHLGN 82
            ||:|..:     :|:|                           .|||...|.:|.|.|.|:...:
Mouse    27 WNQPPAEVNLSPITIPGTEETMRKKAKEEEGLPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNS 91

  Fly    83 KTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPVRSY 147
            | |||:....  |:..|...::.|.|.:.. .|...|::|:|:.....|.|.|.|.:.||.
Mouse    92 K-VAWLNRSG--IIFAGHDKWSLDPRVELE-KRHALEYSLRIQKVDVYDEGSYTCSVQTQH---- 148

  Fly   148 SVNLNIVDLIDAETSDIMQQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDL 212
                      :.:||.:          |:                     .|.||........|:
Mouse   149 ----------EPKTSQV----------YL---------------------IVQVPPKISNISSDV 172

  Fly   213 YVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLH 277
            .|::||.:.|.|:....|||.  |.|.|... |..|..|         .||...||.|...   .
Mouse   173 TVNEGSNVTLVCMANGRPEPV--ITWRHLTP-LGREFEG---------EEEYLEILGITRE---Q 222

  Fly   278 SGKYSCYPSNTEIASIRV 295
            ||||.|..:| |::|..|
Mouse   223 SGKYECKAAN-EVSSADV 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	24/79 (30%)
		IG_like	210..297	CDD:214653	29/86 (34%)
		IGc2	217..287	CDD:197706	23/69 (33%)
Lsamp	XP_030104997.1	Ig	69..159	CDD:386229	29/138 (21%)
		Ig_3	163..232	CDD:372822	25/83 (30%)
		Ig_3	250..325	CDD:372822
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910