DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr10 and LRIT1

DIOPT Version :9

Sequence 1:NP_729591.1 Gene:dpr10 / 39180 FlyBaseID:FBgn0052057 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens


Alignment Length:335 Identity:60/335 - (17%)
Similarity:104/335 - (31%) Gaps:90/335 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 NITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDID----EWT- 121
            :|.||:|.:|.|.|....:....::|.|              ...:....:.|:::.    .|| 
Human   262 SIRSLLGGTALLRCGATGVPGPEMSWRR--------------ANGRPLNGTVHQEVSSDGTSWTL 312

  Fly   122 LQIKWAQQRDAGVYECQISTQPVRSYSVNLNIVDLIDAETSDIMQQYYNDDAFYI-----AENRV 181
            |.:......|:|.|.||..    .....:..::.||..|.....:...:..|.:.     .|...
Human   313 LGLPAVSHLDSGDYICQAK----NFLGASETVISLIVTEPPTSTEHSGSPGALWARTGGGGEAAA 373

  Fly   182 YQSSNDEFAGMFGPIQTVAVPTATILG-GPDLYVDKGSTINLTCIIKFSPEP----------PTH 235
            |   |::......|    .:|...:|. ||.:    .||.....:..|..:.          |:.
Human   374 Y---NNKLVARHVP----QIPKPAVLATGPSV----PSTKEELTLEHFQMDALGELSDGRAGPSE 427

  Fly   236 IFWYHQDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLHSGKYSCYPSNTEIASIRVHVLQG 300
            .......||:.:......|.:|..:::.|.:..::|.....|              |:|..::|.
Human   428 ARMVRSVKVVGDTYHSVSLVWKAPQAKNTTAFSVLYAVFGQH--------------SMRRVIVQP 478

  Fly   301 ERPEAMQTNAAPAAVALACWSCHFG--------------------QATQAVRVISTMVA-----A 340
            .:.....|...|....:|| .|..|                    ...|.:.|:...||     .
Human   479 GKTRVTITGLLPKTKYVAC-VCVQGLVPRKEQCVIFSTNEVVDAENTQQLINVVVISVAIVIALP 542

  Fly   341 LVLLEACSSL 350
            |.||..||:|
Human   543 LTLLVCCSAL 552

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr10NP_729591.1 Ig 63..143 CDD:299845 18/84 (21%)
IG_like 210..297 CDD:214653 14/96 (15%)
IGc2 217..287 CDD:197706 11/79 (14%)
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 16/95 (17%)
IG_like 267..345 CDD:214653 16/95 (17%)
FN3 431..498 CDD:214495 14/81 (17%)
LRR 6. /evidence=ECO:0000305 571..594
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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