Protein Alignment dpr10 and NEGR1

DIOPT Version :9

• Sequence 1: NP_729591.1
• Gene: dpr10 / 39180
• FlyBaseID: FBgn0052057
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 76/369 - (20%)
• Similarity: 115/369 - (31%)
• Gaps: 153/369 - (41%)

  Fly    41 PSHYPHGHKWNEPY--FDLTMPRNITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTY 103
            ||..|.|...:.|:  .|..|.|.     |.:|.|.|.::. |....||:....  |:..|...:
Human    29 PSCLPAGQSVDFPWAAVDNMMVRK-----GDTAVLRCYLED-GASKGAWLNRSS--IIFAGGDKW 85

  Fly   104 TTDQR--FQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPV-RSYSVNLNIVDLIDAETSDIM 165
            :.|.|  ..|...||   ::|||:.....|.|.|.|.:.||.. |:..|:|.:.
Human    86 SVDPRVSISTLNKRD---YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQ----------- 136

  Fly   166 QQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSP 230
                       ...::|..||                        |:.|::|:.:.|||:....|
Human   137 -----------VPPKIYDISN------------------------DMTVNEGTNVTLTCLATGKP 166

  Fly   231 EPPTHIFWYH--------------------QDK----------------------------VLSE 247
            ||  .|.|.|                    :|:                            .:.|
Human   167 EP--SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQE 229

  Fly   248 ETSG----GRL-------------KFKTIKSEE---------------TKSILLIYDADLLHSGK 280
            ..||    ||.             .|:..|.|:               |:|||.:.:....|.|.
Human   230 IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGN 294

  Fly   281 YSCYPSN---TEIASIRVHVLQGERPEAMQTNAAPAA-VALACW 320
            |:|..:|   |..||:.::     .|...|.....:| |..:||
Human   295 YTCVAANKLGTTNASLPLN-----PPSTAQYGITGSADVLFSCW 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	22/81 (27%)
		IG_like	210..297	CDD:214653	33/169 (20%)
		IGc2	217..287	CDD:197706	27/149 (18%)
NEGR1	NP_776169.2	IG	47..135	CDD:214652	28/98 (29%)
		IGc2	152..210	CDD:197706	11/59 (19%)
		Ig_3	225..301	CDD:372822	16/75 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810