DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr10 and Iglon5

DIOPT Version :9

Sequence 1:NP_729591.1 Gene:dpr10 / 39180 FlyBaseID:FBgn0052057 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:297 Identity:71/297 - (23%)
Similarity:116/297 - (39%) Gaps:66/297 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 NITSLVGKSAYLGCRV-KHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIK 125
            |.|...|.:|.|.|.: :|:  ..|||:...  :||..|...:|:|.|.:...:.. :|:::.|.
Mouse    41 NYTVCEGDNATLSCFIDEHV--TRVAWLNRS--NILYAGNDRWTSDPRVRLLINTP-EEFSILIT 100

  Fly   126 WAQQRDAGVYECQISTQ--------------PVRSYSV----------NLNIVDLIDAETSDIMQ 166
            .....|.|:|.|...|:              |.|..::          |:|::.|........:.
Mouse   101 QVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVAVNEGGNVNLLCLAVGRPEPTVT 165

  Fly   167 QYYNDDAFYIAENRVYQSSNDEFAGMFGPIQ------------------TVAVPTATILGGPDLY 213
            .....|.| .:|..:.:.| |...|..|..:                  ||..| .||.......
Mouse   166 WRQLRDGF-TSEGEILEIS-DIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYP-PTITDVTSAR 227

  Fly   214 VDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLHS 278
            ...|....|.|  :....||....||..|::||..::.| ||   :::|.|:|:||..:....|.
Mouse   228 TALGRAALLRC--EAMAVPPADFQWYKDDRLLSSGSAEG-LK---VQTERTRSMLLFANVSARHY 286

  Fly   279 GKYSCYPSN---TEIASIRVHVLQGERPEAMQTNAAP 312
            |.|:|..:|   ...||:|:     .||.::: |:||
Mouse   287 GNYTCRAANRLGASSASMRL-----LRPGSLE-NSAP 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr10NP_729591.1 Ig 63..143 CDD:299845 22/94 (23%)
IG_like 210..297 CDD:214653 26/89 (29%)
IGc2 217..287 CDD:197706 22/69 (32%)
Iglon5NP_001157990.1 Ig 41..129 CDD:416386 23/92 (25%)
Ig strand A' 41..46 CDD:409353 2/4 (50%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/3 (0%)
FR2 61..68 CDD:409353 3/6 (50%)
Ig strand C 61..67 CDD:409353 3/5 (60%)
CDR2 69..79 CDD:409353 3/11 (27%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 9/35 (26%)
Ig strand D 84..91 CDD:409353 1/6 (17%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 0/8 (0%)
FR4 122..129 CDD:409353 0/6 (0%)
Ig strand A 132..137 CDD:409353 2/4 (50%)
Ig_3 134..199 CDD:404760 11/66 (17%)
Ig strand A' 140..145 CDD:409353 0/4 (0%)
Ig strand B 148..157 CDD:409353 3/8 (38%)
Ig strand C 163..167 CDD:409353 0/3 (0%)
Ig strand D 174..177 CDD:409353 0/2 (0%)
Ig strand E 178..183 CDD:409353 0/4 (0%)
Ig strand F 191..199 CDD:409353 1/7 (14%)
Ig_3 217..295 CDD:404760 25/84 (30%)
putative Ig strand A 218..224 CDD:409353 2/5 (40%)
Ig strand B 234..238 CDD:409353 1/3 (33%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Ig strand G 301..304 CDD:409353 1/2 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.