DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and zig-4

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	140	Identity:	32/140 - (22%)
Similarity:	47/140 - (33%)	Gaps:	43/140 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 PIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLS-------EETSGG 252
            |:::..:|             .|.|..|.|.|..:|....|  |....|::.       ||.
Worm    51 PLESALIP-------------GGETYQLRCDIMSTPAATIH--WKFNGKLIQGSNELNVEEK--- 97

  Fly   253 RLKF--KTIKSEETKSILLIYDADLLHSGKYSC--YPSNTEIASIRVHVLQGERPEAMQTNAAPA 313
            .|.|  ..:.:....|||.|......:||.|||  |..:..|.::....::||
Worm    98 LLNFGKAIVDTGIVASILTIQCPSAENSGTYSCVGYNGHQTIETVAEVEIEGE------------ 150

  Fly   314 AVALACWSCH 323
              |..|.|.|
Worm   151 --ASGCRSNH 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845
		IG_like	210..297	CDD:214653	24/97 (25%)
		IGc2	217..287	CDD:197706	23/80 (29%)
zig-4	NP_509335.1	I-set	47..147	CDD:254352	26/113 (23%)
		Ig	65..144	CDD:143165	22/83 (27%)
		IG_like	176..245	CDD:214653
		Ig	<193..238	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900