DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and rig-3

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_509155.1	Gene:	rig-3 / 180958	WormBaseID:	WBGene00004370	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	275	Identity:	40/275 - (14%)
Similarity:	73/275 - (26%)	Gaps:	115/275 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 GHKWNEPYFDLT------MPRNITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTT 105
            |....||...:|      :...|.::.|..|.:....|.....||:.|        |:..:..|:
Worm   171 GPSGKEPMIQMTNGNGEPLDEEIWTIAGNEATIDSLKKEHAELTVSCI--------TIEMHQETS 227

  Fly   106 DQRFQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPVRSYSVNLNIVDLIDAETSDIMQQYYN 170
            .:.|.....:|                                ||:.:..|.:.||.:.:|
Worm   228 KEEFPVVDRKD--------------------------------VNIEVYTLPEFETEESVQ---- 256

  Fly   171 DDAFYIAENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTH 235
               :.:.:|.|..:.                                    :.|.:..|..|..|
Worm   257 ---YTVIDNHVRDAI------------------------------------IYCNVTHSFPPVRH 282

  Fly   236 IFWYHQDKVLSEE-----------TSGGRLKFKTIKSEETKSILLIYDADLLHSGKYSCYPSNTE 289
            ..:||.|:.:...           :.|..||...:...:.              |.|.|..:|.:
Worm   283 YTFYHGDEEIKMSDKFNIFVNVGVSQGAHLKIHNVNENDL--------------GTYKCEANNIK 333

  Fly   290 IASIR-VHVLQGERP 303
            ..|.. :|:.:...|
Worm   334 AKSYHTIHLREANAP 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	11/79 (14%)
		IG_like	210..297	CDD:214653	15/98 (15%)
		IGc2	217..287	CDD:197706	13/80 (16%)
rig-3	NP_509155.1	IG_like	48..142	CDD:214653
rig-3	NP_509155.1	Ig	267..341	CDD:319273	15/123 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900