DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and igcm-2

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001362087.1	Gene:	igcm-2 / 180913	WormBaseID:	WBGene00020130	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	341	Identity:	60/341 - (17%)
Similarity:	116/341 - (34%)	Gaps:	108/341 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFCCLTGLAVCYQRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAY 72
            |:.|   |||     ::..|:.::.:.:.|.|             ...|| :|.|.|.:.|.:.:
Worm   184 LYTC---LAV-----NIEGNSTSSIDVRFTKA-------------TILDL-IPLNKTVIEGSNVF 226

  Fly    73 LGCRVKHLGNKTVA----WI-RHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDA 132
            ..|   |...:..|    |: ..:.:...::|             ...:|....|.::..::.|:
Worm   227 WHC---HANAQATAISYSWLFEKKPIKTTSLG-------------LRSNIRSGDLSLQDVRKSDS 275

  Fly   133 GVYECQI------------------------STQPVRSYSVNLNIVDLIDAETSDIMQQY-YNDD 172
            |.|.|:.                        |.|||::.:...|.....|...:.....| ::.:
Worm   276 GWYTCEAKNSAGETTSSTAYLHVFYPPEPLSSHQPVQTVASGRNTTVSCDVIANPTPTSYTWSKN 340

  Fly   173 AFYI---------------AENRVYQSSNDEFAGMFGPIQTVAV----PTATILGGPDLYVDKGS 218
            ..|:               .:..:|....|..||....::|..:    |..|:....::.|..|.
Worm   341 GHYLPTQASSHIIISYAKPGDGGIYGCQADNIAGKGSIVETHLIVAEPPVFTVAPPSEIKVRLGD 405

  Fly   219 TINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLHSGKYSC 283
            .:::.|  :...:|...::|....|.:::.|    |.||.::.              |..|.|.|
Worm   406 QVSIPC--QGFGDPMPIVYWIRDKKRINQST----LTFKKVEH--------------LDHGAYEC 450

  Fly   284 YPSNT-EIASIRVHVL 298
            ..:|: |..|.||.:|
Worm   451 VVANSVETISTRVMLL 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	14/108 (13%)
		IG_like	210..297	CDD:214653	19/87 (22%)
		IGc2	217..287	CDD:197706	13/69 (19%)
igcm-2	NP_001362087.1	IG_like	23..101	CDD:214653
		Ig	124..200	CDD:386229	6/23 (26%)
		IG_like	214..298	CDD:214653	15/99 (15%)
		Ig_3	309..371	CDD:372822	8/61 (13%)
		Ig	389..467	CDD:386229	22/98 (22%)
		FN3	476..548	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900