DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr10 and rig-5

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001251131.1	Gene:	rig-5 / 172791	WormBaseID:	WBGene00004372	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	289	Identity:	58/289 - (20%)
Similarity:	101/289 - (34%)	Gaps:	90/289 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFCCLTGLAVCYQRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAY 72
            ||..|.|:.:.: :|:.|..      |.||...||                 ..:..:|:|:...
Worm    63 LFALLCGVLLVF-KQACSRG------APPTIQQPS-----------------MSSAVALLGQDVD 103

  Fly    73 LGCRVKHLGNKTVAWIR-HRDLHILTVGTYTYTTDQRFQT-----SYHRDIDEWTLQIKWAQQRD 131
            ..|.|..||:..||::: .....:|:.....:....:::.     ..|   :||.|.||..|:.|
Worm   104 FTCIVNDLGSHMVAFVKADSPPRLLSFDEKVFRRRNKYELKPRIGDLH---NEWVLTIKNVQESD 165

  Fly   132 AGVYECQISTQPVRSYSVNLNIVDLIDAETSDIMQQYYNDDAFYIAENRVYQSSNDEFAGMFGPI 196
            .|.|.|||:|:|:...:..|::                                      ...|:
Worm   166 RGNYSCQINTEPITLSTGELDV--------------------------------------KVPPV 192

  Fly   197 QTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVL---SEETSGGRLKFKT 258
            .:.:.|.|       :.|.:|:.::|||....:|.|.  :.|..||:.:   :..|..|...|.
Worm   193 VSRSTPAA-------VEVREGNNVSLTCKADGNPTPT--VIWRRQDRQIIRYNGATGFGASVFH- 247

  Fly   259 IKSEETKSILLIYDADLLHSGKYSCYPSN 287
                  ..:|.:......|..:|.|..||
Worm   248 ------GPVLHLTKVSRKHMSEYLCVASN 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	23/85 (27%)
		IG_like	210..297	CDD:214653	19/81 (23%)
		IGc2	217..287	CDD:197706	16/72 (22%)
rig-5	NP_001251131.1	IG_like	92..189	CDD:214653	25/137 (18%)
		Ig_3	191..270	CDD:372822	20/94 (21%)
		IG	294..380	CDD:214652
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910