DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and si:ch211-264f5.6

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_002665524.2	Gene:	si:ch211-264f5.6 / 100319064	ZFINID:	ZDB-GENE-081104-208	Length:	540	Species:	Danio rerio

Alignment Length:	385	Identity:	73/385 - (18%)
Similarity:	120/385 - (31%)	Gaps:	119/385 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ITSLVGKSAYLGCRVKHLGN-KTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDID----EWTL 122
            |..:|||:......|....: .||.|..::...|..|.....:.....:..|...|.    .:.|
Zfish    31 INGVVGKNVTFKTTVVSTPDILTVTWTFNKGQPIAMVTVIPSSNTVSVRPPYVNRISCNRTTFQL 95

  Fly   123 QIKWAQQRDAGVYECQIST---------------QPVRSYSVNLNIVDLIDAETSDIM------- 165
            |:....:.|.|.|...|.|               :||....::.|:::.::..::.::
Zfish    96 QLGPLVKEDTGEYILTIVTNNGDLVTGQIDLEVLEPVTDVKISSNVLEPVEFNSTVVLTCSAKGS 160

  Fly   166 --QQYYND------DAFYIAENRV---YQSSNDEFAGMFGPIQTVA---------VP-TATILGG 209
              .::.|.      |..::..|.|   .:.|......:.|||..:|         .| ..|:..|
Zfish   161 FTYKWINGSVPLVVDGTHMQLNAVGNELKISEVRRTDLQGPIVCIAENALESGKSAPFNLTVSYG 225

  Fly   210 P----------DLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEET 264
            |          |.|:.||||:.|||..  ...||..|.|......|..........| |:.:.|.
Zfish   226 PENILMNQFPTDTYLKKGSTLTLTCTA--DSNPPATIQWVFNGVNLPSNAVSSPANF-TLNNLEE 287

  Fly   265 KSILLIYDADLLHSGKYSCYPSNTEIASIRVHVLQGERPEAMQTNAAPAAVALACWSCHFGQATQ 329
            |           :||.|:|...|                                        .|
Zfish   288 K-----------NSGNYTCVAYN----------------------------------------AQ 301

  Fly   330 AVRVISTMVAALVLLEACSSLLLQSGGGGGCPGGGS------PAGGMPTRVREIRE-KPL 382
            ..|.|::.||.:.::|:.|...:.|.......|..:      .|.|....|..::: |||
Zfish   302 TKRYIASRVAFVTVVESLSGTNISSSTSLLIAGNSTVNLTCFAAAGRAETVEWVKDGKPL 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	19/99 (19%)
		IG_like	210..297	CDD:214653	24/96 (25%)
		IGc2	217..287	CDD:197706	19/69 (28%)
si:ch211-264f5.6	XP_002665524.2	Ig	33..129	CDD:299845	18/95 (19%)
		IG_like	33..128	CDD:214653	18/94 (19%)
		Ig	130..222	CDD:299845	13/91 (14%)
		IG_like	149..222	CDD:214653	10/72 (14%)
		I-set	233..315	CDD:254352	28/135 (21%)
		Ig_2	235..315	CDD:290606	28/133 (21%)
		IGc2	335..398	CDD:197706	6/27 (22%)
		Ig_2	427..494	CDD:290606
		IG_like	427..479	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910