Protein Alignment Srg2 and HXT4

DIOPT Version :10

• Sequence 1: NP_729590.1
• Gene: Srg2 / 39179
• FlyBaseID: FBgn0262007
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_011960.2
• Gene: HXT4 / 856492
• SGDID: S000001134
• Length: 576
• Species: Saccharomyces cerevisiae
• Alignment Length: 568
• Identity: 118/568 - (20%)
• Similarity: 204/568 - (35%)
• Gaps: 158/568 - (27%)

  Fly    40 TPAETYGPQPPPMPPRDPHTRVDPPGGCFQRN-----QKNKPQSN--------------AVGAAG 85
            |||:...|     ...|.::.:..|....:|:     .:|..:||              .|....
Yeast    16 TPADALSP-----VESDSNSALSTPSNKAERDDMKDFDENHEESNNYVEIPKKPASAYVTVSICC 75

  Fly    86 LIFISGGMNIAWAIGFQGPIYYQT-------TKHN----YIA----------WFIGAIIGALVTM 129
            |:...||....|..|.......||       .||:    |::          :.||..||.::..
Yeast    76 LMVAFGGFVFGWDTGTISGFVAQTDFIRRFGMKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILA 140

  Fly   130 ALTNKVAKKYILQFSSVLVTVGGLVIACTHN-----------NGAGTTAACYLDGIANGLVFAPF 183
            .|.:...:|..|....|:..:|.::...:.|           :|.|      :.|||   |.:|.
Yeast   141 KLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLG------VGGIA---VLSPM 196

  Fly   184 MALVGEISVPYLRGKASATLEQLCFGTGILLQILYVSNWTYSSYMTYNDFTSENMKGVLSTIYG- 247
              |:.|:|..::|| ...:..||....||.|.  |.:|:...:|.     .|...:..|...:.
Yeast   197 --LISEVSPKHIRG-TLVSCYQLMITLGIFLG--YCTNYGTKTYT-----NSVQWRVPLGLGFAW 251

  Fly   248 VLALIMGSFFTIESPVLMLANNEEQAAIDALRR---------LQKPAVLTE-ETYELLAEHKRYL 302
            .|.:|.|..|..|||..::    |...|:..:|         ...|||:.| |..:...|.::..
Yeast   252 ALFMIGGMTFVPESPRYLV----EVGKIEEAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLA 312

  Fly   303 AYNKNMSKSESISKALPTFMRL---AYLRALNAMSISSFVIITYVVAILVSNDLRNASSWYIGLA 364
            .   |.|..|..|.....|.||   |.:::|..::..:: ...|...:..:..|.::....|.|.
Yeast   313 G---NASWGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNY-FFYYGTTVFTAVGLEDSFETSIVLG 373

  Fly   365 FCRWLGSLIPSFCMESLGRKKPAVFGL--LVSCGLSFA-VGSQYNVYTYMSQVTVL--------- 417
            ...:..:.:..|.:|..||::..::|.  :.:|.:.|| ||           ||.|
Yeast   374 IVNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVG-----------VTRLWPNGKKNGS 427

  Fly   418 -------IMIFEFFAGMAFSSNSAYL-----TEAYPMGVKQHFIGLT--------FITEIFVFLI 462
                   :::|..|....|::..|.:     :|.:|:.||...:.:.        |:...|...|
Yeast   428 SKGAGNCMIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIGFFTPFI 492

  Fly   463 INVCDFNFG---QG---YNYFYIMGAMYLAGVILGVLTLPETRRMTLQ 504
            ....||.:|   .|   ::|||:.            ..:|||:.:||:
Yeast   493 SGAIDFYYGYVFMGCLVFSYFYVF------------FFVPETKGLTLE 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srg2	NP_729590.1	DUF2076	<6..>42	CDD:430876	1/1 (100%)
		MFS	115..504	CDD:475125	96/461 (21%)
HXT4	NP_011960.2	Sugar_tr	74..534	CDD:395036	107/505 (21%)