DRSC/TRiP Functional Genomics Resources

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Protein Alignment Srg2 and Slc2a1

DIOPT Version :10

Sequence 1:NP_729590.1 Gene:Srg2 / 39179 FlyBaseID:FBgn0262007 Length:518 Species:Drosophila melanogaster
Sequence 2:NP_035530.2 Gene:Slc2a1 / 20525 MGIID:95755 Length:492 Species:Mus musculus


Alignment Length:506 Identity:112/506 - (22%)
Similarity:186/506 - (36%) Gaps:116/506 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 AVGAAGLIFISGGMNIAWAIG-FQGP------IYYQTTKHNY----------------IAWF-IG 120
            |||.|    :.|.:...:..| ...|      .|.||..|.|                :|.| :|
Mouse    15 AVGGA----VLGSLQFGYNTGVINAPQKVIEEFYNQTWNHRYGEPIPSTTLTTLWSLSVAIFSVG 75

  Fly   121 AIIGALVTMALTNKVAKKYILQFSSVLVTVGGLVIACTHNNGAGTT-----AACYLDGIANGLV- 179
            .:||:.......|:..::..:...::|..|..:::..:.   .|.:     ...::.|:..||. 
Mouse    76 GMIGSFSVGLFVNRFGRRNSMLMMNLLAFVAAVLMGFSK---LGKSFEMLILGRFIIGVYCGLTT 137

  Fly   180 -FAPFMALVGEISVPYLRGKASATLEQLCFGTGILLQILYVSNWTYSSYMTYNDFTSENMKGVLS 243
             |.|.  .|||:|...||| |..||.||    ||::.||....:...|.|...|.    ...:||
Mouse   138 GFVPM--YVGEVSPTALRG-ALGTLHQL----GIVVGILIAQVFGLDSIMGNADL----WPLLLS 191

  Fly   244 TIYGVLALIMGSF--FTIESPVLMLAN-NEEQAAIDALRRLQKPAVLTEETYELLAEHKRYLAYN 305
            .|: :.||:....  |..|||..:|.| |||..|...|::|:..|.:|.:..|:..|       .
Mouse   192 VIF-IPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEE-------G 248

  Fly   306 KNMSKSESISKALPTFMRLAYLRALNAMSISSFVIITYVVAILVSNDLR--NASSWY-------- 360
            :.|.:.:.:: .|..|...||.:.           |...|.:.:|..|.  ||..:|        
Mouse   249 RQMMREKKVT-ILELFRSPAYRQP-----------ILIAVVLQLSQQLSGINAVFYYSTSIFEKA 301

  Fly   361 ---------IGLAFCRWLGSLIPSFCMESLGRKKPAVFGL--LVSCG----LSFAVGSQYNVYTY 410
                     ||........:::..|.:|..||:...:.||  :..|.    ::.|:..:....:|
Mouse   302 GVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLERLPWMSY 366

  Fly   411 MSQVTVLIMIFEFFAGMAFSSNSA---YLTEAYPMGVKQHFIGLTFITEIFVFLIINVCDFNFGQ 472
            :|    ::.||.|.|.........   .:.|.:..|.:...|.:...:......|:.:| |.:.:
Mouse   367 LS----IVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMC-FQYVE 426

  Fly   473 ---GYNYFYIMGAMYLAGVILGVLTLPETRRMTL--------QGAQEQFNK 512
               |...|.|...:.:...|.....:|||:..|.        ||...|.:|
Mouse   427 QLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDK 477

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Srg2NP_729590.1 DUF2076 <6..>42 CDD:430876
MFS 115..504 CDD:475125 96/438 (22%)
Slc2a1NP_035530.2 MFS_GLUT_Class1 14..458 CDD:340989 107/485 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 468..492 4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

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