DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and HXT5

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_011964.1	Gene:	HXT5 / 856496	SGDID:	S000001138	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	556	Identity:	115/556 - (20%)
Similarity:	213/556 - (38%)	Gaps:	143/556 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DAEQHIHRNSDRQRELILQNSQT-----SPCCNRDLRNQPQANAVGAAALIFLTGGVHIAWSIG- 78
            |..:.:.:..|:|.|   :.|::     |.||                 |:...||....|..|
Yeast    62 DELEELQKEVDKQLE---KKSKSDLLFVSVCC-----------------LMVAFGGFVFGWDTGT 106

  Fly    79 -------------FDSS-------LSELEVTNHVQI----CWFIGAIIGALLGGFFSRWFPYKTL 119
                         |.|:       ||::.....|.|    | .||.|:.:.||..:.|.....|:
Yeast   107 ISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGC-AIGGIVLSKLGDMYGRKIGLMTV 170

  Fly   120 MEFCSLITITGGIVMAVNRMD-LDALLAGRYMNGLANG--LAIAPTLAMAGELSVFYKRGTTTSA 181
            :...|:     ||::.:..:| ......||.::||..|  ..:||.|  ..|:|....|||..|
Yeast   171 VVIYSI-----GIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPML--ISEVSPKQLRGTLVS- 227

  Fly   182 AEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSGVLGSIALLLAFLLSI----------ESP 236
            ..|...|.|||:. .|       ::|..:.:.   :.|...:.|.|.|..||          |||
Yeast   228 CYQLMITFGIFLG-YC-------TNFGTKNYS---NSVQWRVPLGLCFAWSIFMIVGMTFVPESP 281

  Fly   237 VDLLEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHR---SMGWRHAL---PALVRLS 295
            ..|:|.|..:.|.::|:|..:....:.....::.::::.:|..|   |..|...:   |.:.| .
Yeast   282 RYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGKPQMFR-R 345

  Fly   296 VLRALYALSLSVMVA----FTLAWTSTEVYG--DSSGPYVLFGFLRLMGSFTTSFALDSLGRKIP 354
            .|..:...||..:..    |....|..:..|  ||....::.|.:..:.:|.:.:.:|..||:..
Yeast   346 TLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGLEDSFETAIVLGVVNFVSTFFSLYTVDRFGRRNC 410

  Fly   355 LLLGLVISGCLACGL------------------ASRFAGSHPLTFSGNRMALWLLLIYQLFAGIA 401
            ||.|.|  |.:.|.:                  :|:.||:..:.|:    ..::......:|.:|
Yeast   411 LLWGCV--GMICCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFA----CFYIFCFATTWAPVA 469

  Fly   402 FAPSSSYLSEAFPRRIKRPCIAIT--------YILEIIVQLLLRQMDFAAIGSDSSYVALYFFIL 458
            :.    .:||::|.|::...::|.        :::......:...::|           .|.::.
Yeast   470 YV----LISESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAINF-----------YYGYVF 519

  Fly   459 GGLLLAGFLFSVWYMPETKDTTLLQAQFKFQEFVIP 494
            .|.::..:.:..:::||||..||.:....::|.|:|
Yeast   520 MGCMVFAYFYVFFFVPETKGLTLEEVNEMYEENVLP 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	92/430 (21%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	106/518 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342690
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740