DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and HXT17

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_014470.1	Gene:	HXT17 / 855809	SGDID:	S000005355	Length:	564	Species:	Saccharomyces cerevisiae

Alignment Length:	588	Identity:	121/588 - (20%)
Similarity:	209/588 - (35%)	Gaps:	184/588 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 QTSPCCNRDLRNQPQANAVGAAALIFLTGGVHIA------WSIGFDSSLSELEVTNHVQI----C 95
            |:|...:||:::.|.|:             :|:|      ||.|||.:    ||.|...:    .
Yeast     2 QSSTESDRDIQDGPDAD-------------IHVAPPVEKEWSDGFDDN----EVINGDNVEPPKR 49

  Fly    96 WFIGAIIGALL------GGFFSRW--------------------FPYKT------------LMEF 122
            ..||.::..||      |||...|                    :.:.|            |:..
Yeast    50 GLIGYLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAM 114

  Fly   123 CSLITITGGIVMAVNRMDLDALLA---------------------------GRYMNGLANG---- 156
            .|:....||::.|.....|...||                           |:.:.||..|
Yeast   115 FSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSV 179

  Fly   157 ------LAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGV 215
                  ..||||....|.:|::           |...|.|||:. .||.....:.|.|.:....:
Yeast   180 LCPMLLSEIAPTDLRGGLVSLY-----------QLNMTFGIFLG-YCSVYGTRKYDNTAQWRVPL 232

  Fly   216 LSGVLGSIALLLAFLLSIESPVDLLEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHR 280
            ....|.::.:::..||..|||..|:|....:.|..:::::.:..........|..:....|...|
Yeast   233 GLCFLWTLIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQR 297

  Fly   281 SMG---WRHALPALVRLSVLRALYALSLSVMVAFTLAWTSTE---VYGDSSGPYVLFGFLRLMGS 339
            .:|   |:....  |:..||:.|..   .::|...|..|...   .||.:     :|..:.|...
Yeast   298 ELGEASWKELFS--VKTKVLQRLIT---GILVQTFLQLTGENYFFFYGTT-----IFKSVGLTDG 352

  Fly   340 FTTSFAL---------------DSLGRKIPLLLGLVISGCLAC------------------GLAS 371
            |.||..|               |.:||:..||.|  .:|.:||                  |.:|
Yeast   353 FETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFG--AAGMMACMVIFASIGVKCLYPHGQDGPSS 415

  Fly   372 RFAGSHPLTFSGNRMALWLLLIYQLFAGIAFAPSSSYLSEAFPRRIKRPCIAITYILEIIVQLLL 436
            :.||:..:.|:    ..::......:|.:|:.    .::|:||.::|...::|:.....:.|.|:
Yeast   416 KGAGNAMIVFT----CFYIFCFATTWAPVAYI----VVAESFPSKVKSRAMSISTACNWLWQFLI 472

  Fly   437 RQMDFAAIGSDSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTLLQAQFKFQEFV--------I 493
            ........||...|   |.::..|.|:|.||:..:::|||...:|.:.|..::|.:        :
Yeast   473 GFFTPFITGSIHFY---YGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWV 534

  Fly   494 PPA 496
            ||:
Yeast   535 PPS 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	95/478 (20%)
HXT17	NP_014470.1	Sugar_tr	60..521	CDD:395036	99/495 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342687
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740