Protein Alignment CG32053 and ITR2

DIOPT Version :9

• Sequence 1: NP_729587.1
• Gene: CG32053 / 39178
• FlyBaseID: FBgn0052053
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 558
• Identity: 103/558 - (18%)
• Similarity: 184/558 - (32%)
• Gaps: 152/558 - (27%)

  Fly     9 DDGFHVV-PIHSDAEQHIHRNSDRQRELILQNSQTSPCCNRDLRNQPQANAVGAAALIFLT---- 68
            |||..|: |::.:.:..:         :|..|...||                  .:|.||
Yeast    80 DDGRIVIKPVNDEDDTSV---------IITFNQSISP------------------FIITLTFVAS 117

  Fly    69 -GGVHIAWSIGFDSS---------------LSELEVTNHVQICWFIGAIIGALLGGFFSRWFPYK 117
             .|....:..|:.||               ..|.|:   :.....:||:|.::..|..:..|..:
Yeast   118 ISGFMFGYDTGYISSALISINRDLDNKVLTYGEKEL---ITAATSLGALITSVGAGTAADVFGRR 179

  Fly   118 TLMEFCSLITITGGIVMAVNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAA 182
            ..:.|.:|:.:.|.| :.:.......:.|||.:.|...|:....:.....|::....||..|...
Yeast   180 PCLMFSNLMFLIGAI-LQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVIN 243

  Fly   183 EQWPTTIGIFVQIVC-------SHSWDVQSDFTEEQFQGVLSGVLGSIALLLAFLLSI---ESPV 237
            ..| .|.|..:...|       .:.|            .:|.| |..|..:|.|....   ::|.
Yeast   244 SLW-LTGGQLIAYGCGAGLNHVKNGW------------RILVG-LSLIPTVLQFSFFCFLPDTPR 294

  Fly   238 DLLEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHRSMG------------WR----- 285
            ..:.:|:.:.|...|.|..      ..|.|::.|.:  ||...|:.            |.
Yeast   295 YYVMKGDLKRAKMVLKRSY------VNTEDEIIDQK--VEELSSLNQSIPGKNPITKFWNMVKEL 351

  Fly   286 HALPALVRLSVLRALYALSLSVMVAFTLAWTS----------TEVYGDSSGPYVLFGFLRLMGSF 340
            |.:|:..|..::    ...|..:..|| .|.|          |..:.:||...::......:.:.
Yeast   352 HTVPSNFRALII----GCGLQAIQQFT-GWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFVFTL 411

  Fly   341 TTSFALDSLGRKIPLLLGL--VISGCLACGLASRFAGSHPLTFSG-------NRMALW------L 390
            ...|.:|.:||:..||:||  :....:.|.:|..|.|   :.|:|       :..:.|      .
Yeast   412 IAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLG---IKFNGADAVVASDGFSSWGIVIIVF 473

  Fly   391 LLIYQLFAGIAFAPSSSYLSEAFPRRIKRPCIAITYI--------LEIIVQLLLRQMDFAAIGSD 447
            :::|..|..:.........||.||:.::.  :..:|.        |.|....|....:....|:
Yeast   474 IIVYAAFYALGIGTVPWQQSELFPQNVRG--VGTSYATATNWAGSLVIASTFLTMLQNITPTGT- 535

  Fly   448 SSYVALYFFILGGLLLAGFLFSVWYMPETKDTTLLQAQ 485
                   |....|:.....:|..:..||.....|.:.|
Yeast   536 -------FSFFAGVACLSTIFCYFCYPELSGLELEEVQ 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	79/429 (18%)
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	87/484 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900