DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and HXT16

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_012692.3	Gene:	HXT16 / 853623	SGDID:	S000003919	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	592	Identity:	113/592 - (19%)
Similarity:	215/592 - (36%)	Gaps:	148/592 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQTERPSPDDGFHVVPIHSD------AEQHIHRNSDRQ-------RELILQNSQTSPCCNRDLRN 52
            |.:|:.||:       |::|      |:.|:....:::       :|:|          |.:..:
Yeast     1 MASEQSSPE-------INADNLNSSAADVHVQPPGEKEWSDGFYDKEVI----------NGNTPD 48

  Fly    53 QPQANAVGAAALIFLT-----GGVHIAWSIG-----------------FDSSLSELEVTN---HV 92
            .|:...:|...:..|.     ||....|..|                 :..|..|..::|   .:
Yeast    49 APKRGFLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGL 113

  Fly    93 QICWF-IGAIIGALLGGFFSRWFPYKTLMEFCSLITITGGIVMAVNRMDLDALLAGRYMNGLANG 156
            .:..| :|..||.:.....:.....:..:....|:.:.|.|:...:.........|:.:.||..|
Yeast   114 LVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAG 178

  Fly   157 ----------LAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQ 211
                      ..||||....|.:|::           |...|.|||:.....:.....|:..:.:
Yeast   179 GCSVLCPMLLSEIAPTDLRGGLVSLY-----------QLNMTFGIFLGYCSVYGTRKYSNTAQWR 232

  Fly   212 FQGVLSGVLGSIALLLAFLLSIESPVDLLEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYV 276
            ....|. .|.::.:::..||..|||..|:|....:.|..:::::.:..........|..:....|
Yeast   233 IPVGLC-FLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKIDKVSPEDPWVLKQADEINAGV 296

  Fly   277 EHHRSMG---WRHALPALVRLSVLRALYALSLSVMVAFTLAWTSTE---VYGDSSGPYVLFGFLR 335
            ...|.:|   |:....  |:..||:.|..   .::|...|..|...   .||.:     :|..:.
Yeast   297 LAQRELGEASWKELFS--VKTKVLQRLIT---GILVQTFLQLTGENYFFFYGTT-----IFKSVG 351

  Fly   336 LMGSFTTSFAL---------------DSLGRKIPLLLGLVISGCLAC------------------ 367
            |...|.||..|               |.:||:..||.|  .:..:||
Yeast   352 LTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFG--AASMMACMVIFASIGVKCLYPHGQD 414

  Fly   368 GLASRFAGSHPLTFSGNRMALWLLLIYQLFAGIAFAPSSSYLSEAFPRRIKRPCIAITYILEIIV 432
            |.:|:.||:..:.|:    ..::......:|.:|:.    .::|:||.::|...::|:.....:.
Yeast   415 GPSSKGAGNAMIVFT----CFYIFCFATTWAPVAYI----VVAESFPSKVKSKAMSISTAFNWLW 471

  Fly   433 QLLLRQMDFAAIGSDSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTLLQAQFKFQEFV----- 492
            |.|:........||...|   |.::..|.|:|.||:..:::|||...:|.:.|..::|.:
Yeast   472 QFLIGFFTPFITGSIHFY---YGYVFVGCLVAMFLYVFFFLPETIGLSLEETQLLYEEGIKPWKS 533

  Fly   493 ---IPPA 496
               :||:
Yeast   534 ASWVPPS 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	78/424 (18%)
HXT16	NP_012692.3	Sugar_tr	63..524	CDD:278511	97/495 (20%)
HXT16	NP_012692.3	MFS	67..510	CDD:119392	91/477 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342691
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740