DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and HXT6

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_010630.1	Gene:	HXT6 / 851944	SGDID:	S000002751	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	503	Identity:	103/503 - (20%)
Similarity:	184/503 - (36%)	Gaps:	100/503 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VGAAALIFLTGGVHIAWSIGFDS------------SLSELEVTNHV------------QICWFIG 99
            |....::...||....|..|..|            .:...:.||::            .|...||
Yeast    65 VSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIG 129

  Fly   100 AIIGALLGGFFSRWFPYKTLMEFCSLITITGGIVMAVNRMDLDALLAGRYMNGL-ANGLAIAPTL 163
            .||.:.||..:.|    |..:....:|.|.|.|:...:.........||.::|| ..|:|:...:
Yeast   130 GIILSKLGDMYGR----KVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPM 190

  Fly   164 AMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSGVLGSIALLLA 228
             :..|:|..:.|||..| ..|...|.|||:. .|       ::|..:.:.   :.|...:.|.|.
Yeast   191 -LISEVSPKHLRGTLVS-CYQLMITAGIFLG-YC-------TNFGTKNYS---NSVQWRVPLGLC 242

  Fly   229 FLLSI----------ESPVDLLEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHRSMG 283
            |..::          |||..|.|.|..:.|.::::...:..........:|......||..:..|
Yeast   243 FAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAG 307

  Fly   284 ---WRHALPALVRLSVLRALYALSLSVMVA-----------FTLAWTSTEVYG--DSSGPYVLFG 332
               |.....     |..:.|..|.:..|:.           |....|..:..|  ||....::.|
Yeast   308 NASWGELFS-----SKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGLSDSFETSIVLG 367

  Fly   333 FLRLMGSFTTSFALDSLGRKIPLLLGLV-ISGCL----ACGL-----------ASRFAGSHPLTF 381
            .:....:|...:.::..||:..||.|.. ::.|:    :.|:           :|:.||:..:.|
Yeast   368 IVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSSKGAGNCMIVF 432

  Fly   382 SGNRMALWLLLIYQLFAGIAFAPSSSYLSEAFPRRIKRPCIAITYILEIIVQLLLRQMDFAAIGS 446
            :    ..::......:|.|.:.    .:||.||.|:|...::|......:...|:........|:
Yeast   433 A----CFYIFCFATTWAPIPYV----VVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGA 489

  Fly   447 DSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTLLQAQFKFQEFVIP 494
            .:.|   |.::..|.|:..|.:.:..:||||..||.:....::|.|:|
Yeast   490 INFY---YGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLP 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	84/421 (20%)
HXT6	NP_010630.1	Sugar_tr	68..528	CDD:278511	99/492 (20%)
HXT6	NP_010630.1	MFS	69..514	CDD:119392	93/477 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342692
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740