DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32053 and SNF3

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_010087.1	Gene:	SNF3 / 851333	SGDID:	S000002353	Length:	884	Species:	Saccharomyces cerevisiae

Alignment Length:	511	Identity:	108/511 - (21%)
Similarity:	192/511 - (37%)	Gaps:	76/511 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RNSDRQREL--ILQNSQTSPCCNRDLRNQP---QANAVGAAALIFL-TGGVHIAWSIGFDSSLSE 85
            :|||||..:  :..:..::...|..|.::|   |:..:.....:|: .||....:..|..:|::.
Yeast    59 QNSDRQSNMTSVFTDDISTIDDNSILFSEPPQKQSMMMSICVGVFVAVGGFLFGYDTGLINSITS 123

  Fly    86 LE-VTNHVQ-------------ICWF--IGAIIGALLGGFFSRWFPYKTLMEFCSLITITGGIVM 134
            :. |.:||.             :..|  :|...|||...|.|..:..|..:.|.::...:.|..:
Yeast   124 MNYVKSHVAPNHDSFTAQQMSILVSFLSLGTFFGALTAPFISDSYGRKPTIIFSTIFIFSIGNSL 188

  Fly   135 AVNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSH 199
            .|....:..|:.||.::|:..|...|.......|.:....||...| ..||..|.|:.|....|.
Yeast   189 QVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATHKSLRGAIIS-TYQWAITWGLLVSSAVSQ 252

  Fly   200 SWDVQSDFTEEQFQGVLSGVLGSIALLLAFLLSIESPVDLLEQGNEQGAVQALSRLQRPRAVTAE 264
            ....::|.:..:....|..|..|...:..|.|. |||...:.:.....|.::||.|:......:.
Yeast   253 GTHARNDASSYRIPIGLQYVWSSFLAIGMFFLP-ESPRYYVLKDKLDEAAKSLSFLRGVPVHDSG 316

  Fly   265 TYDQVRDHRTYVEHHRSMGWRHALPALVRLSVLRALYALSLSVMVAFTLAWTSTEVYGDSSGPYV 329
            ..:::.:.:...::..|.|..:.:...:. |..|....|.:...:|.       :.:...||...
Yeast   317 LLEELVEIKATYDYEASFGSSNFIDCFIS-SKSRPKQTLRMFTGIAL-------QAFQQFSGINF 373

  Fly   330 LF----GFLRLMG-------SFTT-----------SFALDSLGRKIPLLLGLVIS-------GCL 365
            :|    .|....|       ||.|           .|.::..||:..|::|.||.       ..:
Yeast   374 IFYYGVNFFNKTGVSNSYLVSFITYAVNVVFNVPGLFFVEFFGRRKVLVVGGVIMTIANFIVAIV 438

  Fly   366 ACGLASRFAGSHPLTFSGNRMALWLLLIYQLFAGIAFAPSSSYLSEAFPRRIKRPCIAI----TY 426
            .|.|.:..|....:.|    :.|::......:.|:.:..|    :|.:|..::..|.||    .:
Yeast   439 GCSLKTVAAAKVMIAF----ICLFIAAFSATWGGVVWVIS----AELYPLGVRSKCTAICAAANW 495

  Fly   427 ILEIIVQLLLRQMDFAAIGS-DSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTL 481
            ::..|..|:...:  ...|| .||..|..|||.|.|...|.:.....:.|||..||
Yeast   496 LVNFICALITPYI--VDTGSHTSSLGAKIFFIWGSLNAMGVIVVYLTVYETKGLTL 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	78/403 (19%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	99/471 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342611
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830