DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and YDL199C

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_010082.1	Gene:	YDL199C / 851328	SGDID:	S000002358	Length:	687	Species:	Saccharomyces cerevisiae

Alignment Length:	560	Identity:	110/560 - (19%)
Similarity:	204/560 - (36%)	Gaps:	151/560 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VPIHSDAEQHIHRNSDRQRELILQNSQTSPCCNRD--------------LRNQPQANAVGAAALI 65
            :..||.....::|:||  ..::|..|:.:|..:.|              ||::.:.::.......
Yeast    60 ITAHSSRRGSLYRDSD--ATVVLPLSEHTPRLSMDDPYRQLLQQAEISQLRSKKKRHSSRVLRTS 122

  Fly    66 FLTGGVHIAWSIGFDSSLSELEVTN-------HVQICWFIGAIIGAL-LGGFFSRWFPYKTLMEF 122
            |::..|.::...|.|..|....|..       |..:...:|.|:..: ||.|.:..|.|..::|.
Yeast   123 FISFVVLVSSLSGLDQGLISGNVMTLSFQKYFHYPLTSPLGNIVSIVNLGAFMASLFVYSGILEP 187

  Fly   123 CS---------LITITGGI--VMAVNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRG 176
            ||         :|...|.|  |:|:|:.   .||.||::.|:..|.|.:..:....|..:...|.
Yeast   188 CSRKKMLQISTMIYSLGAIVQVLALNQW---CLLLGRFLLGVGMGFAFSMVIIYQFEFPLPCIRK 249

  Fly   177 TTTSAAEQWPTTI----GIFVQIVCSH---SWDVQSDFTEEQFQGVLSGVLGSIALLLAFLLSIE 234
            .|..:.:...:.|    ||::.....:   :|         ::.......||.|..|::|.|.:|
Yeast   250 RTLISIQCVSSVIAYSFGIWINCAFRYLGFAW---------RYPLSTHVALGIILNLMSFYLILE 305

  Fly   235 SPVDLLEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHRSMGWRHALPALVRLSVLRA 299
            ||..||:|.|:..|:..:|              .|.|...:.|:...:.:|     :::..:|..
Yeast   306 SPSWLLKQKNDVEALVLIS--------------NVFDDGNFEENQTQLKFR-----VLKRDILLK 351

  Fly   300 LYALSLSVMVAFTLAWTSTEVYGDSSGPYVLFGFLRLMGS-------FTTSFALDSLGR------ 351
            .:....|...|:.|...|:.:       .:|.||..|..:       :.:...|..:||
Yeast   352 SHLQKNSYPYAYILKDFSSII-------KLLIGFQLLTRTNGVDAFLYYSPLILQQMGRGERKSI 409

  Fly   352 ----------------KIPLLL-------GLVISGCLACGLASRFAGSHPLTFSGNRMALWLLLI 393
                            .:||:|       .:::...:.|.|....:.:.....|..|      .|
Yeast   410 YLTGLNALIYSIVILAYVPLVLRKRKEKTNVLLGSIVMCALLFTISFTDWFPKSTTR------YI 468

  Fly   394 YQLFAGIAFAPSSSYLS-------EAFPRRIKRPCIAIT--------YILEIIVQLLLRQMD--F 441
            ..|||...|....|:.|       |..|...:.|.|.:.        :.:.:|..:|:.::.  |
Yeast   469 SILFAVFLFTHFISWDSIGWVMTIELLPHLSQAPVILLVSNFYWIFKWFVSLITPILIDRLSWKF 533

  Fly   442 AAIGSDSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTL 481
            ..|.|.||::::.|.:.        :|.:    ||:|..|
Yeast   534 YLIPSLSSFISIIFVLK--------IFPI----ETRDERL 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	84/431 (19%)
YDL199C	NP_010082.1	MFS	122..566	CDD:421695	99/496 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900