DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32053 and GAL2

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_013182.1	Gene:	GAL2 / 850770	SGDID:	S000004071	Length:	574	Species:	Saccharomyces cerevisiae

Alignment Length:	550	Identity:	112/550 - (20%)
Similarity:	203/550 - (36%)	Gaps:	112/550 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 HSDAEQHIHRNSD-RQRELILQNSQTSPCCNRDLRNQPQANAVGAAALIFLT--GGVHIAWSIGF 79
            |..|:...:.|.: :..|...:.||:.|.   ::..:|.:..|..:.|....  ||....|..|.
Yeast    30 HLSAQSQKYSNDELKAGESGSEGSQSVPI---EIPKKPMSEYVTVSLLCLCVAFGGFMFGWDTGT 91

  Fly    80 DSS---------------------LSELEVTNHVQICWFIGAIIGALL----GGFFSRWFPYKTL 119
            .|.                     ||.:. |..:...:.||...|.::    |..:.|    |..
Yeast    92 ISGFVVQTDFLRRFGMKHKDGTHYLSNVR-TGLIVAIFNIGCAFGGIILSKGGDMYGR----KKG 151

  Fly   120 MEFCSLITITGGIVMAVNRMDLDALLAGRYMNGL-ANGLAI-APTLAMAGELSVFYKRGTTTSAA 182
            :.....:.|.|.|:...:.........||.::|| ..|:|: .|.|  ..|::..:.|||..| .
Yeast   152 LSIVVSVYIVGIIIQIASINKWYQYFIGRIISGLGVGGIAVLCPML--ISEIAPKHLRGTLVS-C 213

  Fly   183 EQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSGVLG-----SIALLLAFLLSIESPVDLLEQ 242
            .|...|.|||:....::.....|:..:.:..      ||     |:.::.|..|..|||..|.|.
Yeast   214 YQLMITAGIFLGYCTNYGTKSYSNSVQWRVP------LGLCFAWSLFMIGALTLVPESPRYLCEV 272

  Fly   243 GNEQGAVQALSRLQR--PR--AVTAETYDQVRDHRTYVEHHRSMG---WRHALPALVRLSVLRAL 300
            ...:.|.:::::..:  |.  ||.|| .|.:   ...:|..:..|   |........::     .
Yeast   273 NKVEDAKRSIAKSNKVSPEDPAVQAE-LDLI---MAGIEAEKLAGNASWGELFSTKTKV-----F 328

  Fly   301 YALSLSVMVAFTLAWTSTE---VYG----------DSSGPYVLFGFLRLMGSFTTSFALDSLGRK 352
            ..|.:.|.|......|...   .||          ||....::.|.:....:|.:.:.:::||.:
Yeast   329 QRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVGLDDSFETSIVIGVVNFASTFFSLWTVENLGHR 393

  Fly   353 IPLLLGLVISGCLACGLASRFAG---------SHPLTFSGNRMALWLLLIYQLFAGIAFAPSSSY 408
            ..||||  .:..:||.:.....|         |.|.:.......:.....|.......:||.:..
Yeast   394 KCLLLG--AATMMACMVIYASVGVTRLYPHGKSQPSSKGAGNCMIVFTCFYIFCYATTWAPVAWV 456

  Fly   409 L-SEAFPRRIKRPCIAIT--------YILEIIVQLLLRQMDFAAIGSDSSYVALYFFILGGLLLA 464
            : :|:||.|:|..|:|:.        :::......:...::|           .|.::..|.|:|
Yeast   457 ITAESFPLRVKSKCMALASASNWVWGFLIAFFTPFITSAINF-----------YYGYVFMGCLVA 510

  Fly   465 GFLFSVWYMPETKDTTLLQAQFKFQEFVIP 494
            .|.:..:::||||..:|.:.|..::|.|:|
Yeast   511 MFFYVFFFVPETKGLSLEEIQELWEEGVLP 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	85/424 (20%)
GAL2	NP_013182.1	Sugar_tr	74..534	CDD:278511	100/495 (20%)
GAL2	NP_013182.1	MFS	75..518	CDD:119392	93/478 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342685
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740