Protein Alignment CG32053 and SLC2A1

DIOPT Version :9

• Sequence 1: NP_729587.1
• Gene: CG32053 / 39178
• FlyBaseID: FBgn0052053
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 109/490 - (22%)
• Similarity: 193/490 - (39%)
• Gaps: 92/490 - (18%)

  Fly    58 AVGAAALIFL-----TGGVHI-----------AWSIGFDSSLSELEVTN--HVQICWF-IGAIIG 103
            |||.|.|..|     ||.::.           .|...:..|:....:|.  .:.:..| :|.:||
Human    15 AVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIG 79

  Fly   104 ALLGGFFSRWFPYKTLMEFCSLITITGGIVMAVNRM--DLDALLAGRYMNGLANGLAIAPTLAMA 166
            :...|.|...|..:..|...:|:.....::|..:::  ..:.|:.||::.|:..||.........
Human    80 SFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYV 144

  Fly   167 GELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSGVLGSIALLLAFLL 231
            ||:|....||...:..:     :||.|.|:.:..:.:.|....:....:|..::...|||...:|
Human   145 GEVSPTALRGALGTLHQ-----LGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVL 204

  Fly   232 SI--ESPVDLLEQGNEQG-AVQALSRLQRPRAVTAETYDQVRDHR--------TYVEHHRSMGWR 285
            ..  |||..||...||:. |...|.:|:....||.:..:...:.|        |.:|..||..:|
Human   205 PFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYR 269

  Fly   286 HALPALV--------RLSVLRALYALSLSVMVAFTLAWTSTEVYGDSSGPYVLFGFLRLMGSFTT 342
            .  |.|:        :||.:.|::..|.|:   |..|.....||.....     |.:....:..:
Human   270 Q--PILIAVVLQLSQQLSGINAVFYYSTSI---FEKAGVQQPVYATIGS-----GIVNTAFTVVS 324

  Fly   343 SFALDSLGRKIPLLLGLVISGCLACGLASRFAGSHPLTFSGNRMAL-----WL--LLIYQLFAGI 400
            .|.::..||:...|:||  :|...|.:....|           :||     |:  |.|..:|..:
Human   325 LFVVERAGRRTLHLIGL--AGMAGCAILMTIA-----------LALLEQLPWMSYLSIVAIFGFV 376

  Fly   401 AF-----APSSSYL-SEAFPRRIKRPCIAI----TYILEIIVQLLLRQMDFAAIGSDSSYVALYF 455
            ||     .|...:: :|.|.:..:...||:    .:....||.:..:.::...    ..||.:.|
Human   377 AFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLC----GPYVFIIF 437

  Fly   456 FILGGLLLAGFLFSVWYMPETKDTTLLQAQFKFQE 490
            .:   ||:..|:|:.:.:||||..|..:....|::
Human   438 TV---LLVLFFIFTYFKVPETKGRTFDEIASGFRQ 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	86/406 (21%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	107/477 (22%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:24847886	282..288		2/5 (40%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144173
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840