DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32053 and CG10960

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster

Alignment Length:	547	Identity:	117/547 - (21%)
Similarity:	196/547 - (35%)	Gaps:	170/547 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NSDRQRELILQNSQTSPCCNRDLRNQPQANAVGAAALIFLTGGVHIAWSIGFDSSLSELEVTNH- 91
            ::...:|.:|.|...:...|...:......|:.||...|..|.| :.|     :|.:|.|:.:.
  Fly    57 STPHDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAGTV-LGW-----TSPAETEIVDRG 115

  Fly    92 ---------VQICWF-----IGAIIGALLGGFFSRWFPYKTLMEFCSLITITGG--IVMAVNRMD 140
                     .|..|.     :||....:..||.......|..|.|..|..|.|.  ::.|||
  Fly   116 EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN--- 177

  Fly   141 LDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGI-------------F 192
            :..|.|.|::.|:|.|..........||::....|||..|.. |...||||             :
  Fly   178 VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFF-QLMITIGILFVYAVGAGVKIFW 241

  Fly   193 VQIVCSHSWDVQSDFTEEQFQGVLSGVLGSIALLLAFLLSIESPVDLLEQGNEQGAVQALSRLQR 257
            :.|:|                |:|..:.|:|     |....|||..|:.:...:.|::::..|:
  Fly   242 LSIIC----------------GILPLIFGAI-----FFFMPESPTYLVSKDRSENAIKSIQWLR- 284

  Fly   258 PRAVTAETYD------QVRDHRTYVEHHRSMGWRHALPALVRLSVLRALYALSLSVMV------- 309
                 .:.||      ::|:.....:.::...|     |.:...|.|...|:|:.:|.
  Fly   285 -----GKEYDYEPELAELRETDRETKANKVNVW-----AALNRPVTRKALAISMGLMFFQQVCGI 339

  Fly   310 ---------AFTLAWTSTEVYGDSSGPYVLFGFLRLMGSFTTSFALDSLGRKIPLL--------- 356
                     .|..|.|..|    :....:|.|.::::.:|.::..:|.|||:|.||
  Fly   340 NAVIFYASRIFLEANTGIE----AEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAIS 400

  Fly   357 ---LGL-------------------VISGCLACGLASRFAGSHPLTFSGNRMALWLLLIYQLFA- 398
               :|:                   |.|.||...:.|...|..|          ||:: .:|||
  Fly   401 TTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVP----------WLMM-GELFAT 454

  Fly   399 ---GIA--FAPSSSYLSEAFPRRIKRPCIAITYILEIIVQLLLRQMDFAAIGSDSSYVALYFFIL 458
               |.|  .|.:|::|. ||                ::.:..:...|...||..       |::.
  Fly   455 DIKGFAGSLAGTSNWLL-AF----------------VVTKTFVNLNDGLGIGGT-------FWLF 495

  Fly   459 GGLLLAGFLFSVWYMPETKDTTLLQAQ 485
            .||.:.|.:|..:.:||||..:|.:.|
  Fly   496 AGLTVVGVIFVYFAVPETKGKSLNEIQ 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	93/443 (21%)
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	89/424 (21%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	97/464 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444305
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740