DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and CG42825

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_729590.1	Gene:	CG42825 / 39179	FlyBaseID:	FBgn0262007	Length:	518	Species:	Drosophila melanogaster

Alignment Length:	506	Identity:	187/506 - (36%)
Similarity:	286/506 - (56%)	Gaps:	41/506 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PSPDDGFHVVPIHSDAEQ-------HIHRNSDRQRELILQNSQTSPCCNRDLRNQPQANAVGAAA 63
            |.|....|:.|..:...|       ..|...|          ....|..|:.:|:||:||||||.
  Fly    31 PQPGQPQHITPAETYGPQPPPMPPRDPHTRVD----------PPGGCFQRNQKNKPQSNAVGAAG 85

  Fly    64 LIFLTGGVHIAWSIGFDSSLSELEVTNHVQICWFIGAIIGALLGGFFSRWFPYKTLMEFCSLITI 128
            |||::||::|||:|||...: ..:.|.|..|.||||||||||:....:.....|.:::|.|::..
  Fly    86 LIFISGGMNIAWAIGFQGPI-YYQTTKHNYIAWFIGAIIGALVTMALTNKVAKKYILQFSSVLVT 149

  Fly   129 TGGIVMAVNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFV 193
            .||:|:|....:.....|..|::|:||||..||.:|:.||:||.|.||..::..||.....||.:
  Fly   150 VGGLVIACTHNNGAGTTAACYLDGIANGLVFAPFMALVGEISVPYLRGKASATLEQLCFGTGILL 214

  Fly   194 QIVCSHSWDVQS-----DFTEEQFQGVLSGVLGSIALLLAFLLSIESPVDLLEQGNEQGAVQALS 253
            ||:...:|...|     |||.|..:||||.:.|.:||::....:|||||.:|....||.|:.||.
  Fly   215 QILYVSNWTYSSYMTYNDFTSENMKGVLSTIYGVLALIMGSFFTIESPVLMLANNEEQAAIDALR 279

  Fly   254 RLQRPRAVTAETYDQVRDHRTYVEHHRSMGWRH----ALPALVRLSVLRALYALSLS--VMVAFT 312
            |||:|..:|.|||:.:.:|:.|:.::::|....    |||..:||:.||||.|:|:|  |::.:.
  Fly   280 RLQKPAVLTEETYELLAEHKRYLAYNKNMSKSESISKALPTFMRLAYLRALNAMSISSFVIITYV 344

  Fly   313 LAWTSTEVYGDSSGPYVLFGFLRLMGSFTTSFALDSLGRKIPLLLGLVISGCLACGLASRFA-GS 376
            :|...:....::|..|:...|.|.:||...||.::|||||.|.:.||::|    |||:  || ||
  Fly   345 VAILVSNDLRNASSWYIGLAFCRWLGSLIPSFCMESLGRKKPAVFGLLVS----CGLS--FAVGS 403

  Fly   377 HPLTFSGNRMALWLLLIYQLFAGIAFAPSSSYLSEAFPRRIKRPCIAITYILEIIVQLLLRQMDF 441
            ....::.......|::|::.|||:||:.:|:||:||:|..:|:..|.:|:|.||.|.|::...||
  Fly   404 QYNVYTYMSQVTVLIMIFEFFAGMAFSSNSAYLTEAYPMGVKQHFIGLTFITEIFVFLIINVCDF 468

  Fly   442 AAIGSDSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTLLQAQFKFQEFV 492
             ..|...:    ||:|:|.:.|||.:..|..:|||:..||..||.:|.:||
  Fly   469 -NFGQGYN----YFYIMGAMYLAGVILGVLTLPETRRMTLQGAQEQFNKFV 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	138/366 (38%)
CG42825	NP_729590.1	MFS	116..490	CDD:119392	144/384 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438443
Domainoid	1	1.000	93	1.000	Domainoid score	I13956
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I7306
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005925
OrthoInspector	1	1.000	-	-		mtm9616
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.890