DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32053 and CG8249

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster

Alignment Length:	547	Identity:	122/547 - (22%)
Similarity:	200/547 - (36%)	Gaps:	138/547 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DRQRELILQNSQTS--------PCCNRDLRNQP---QANAVGAAALIFLTGGVHIAWSIGF---- 79
            |.|.:.:.||...|        ...:|.|:..|   |..||....:..:...|.: :|.|.
  Fly     2 DEQHQNLNQNGSESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQVIAVILANVGV-FSTGMTLAM 65

  Fly    80 -DSSLSELEVT------NHVQICWF-----IGAIIGALLGGFFSRWFPYKTLMEFCSLITITGGI 132
             .::|.:|:.|      |..|..||     :.|.||.||.||.......|..:...:::.|...|
  Fly    66 PTATLHQLKDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWI 130

  Fly   133 VMAV-NRMDLDA----LLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIF 192
            ::|. :..|.:|    |:..|:|.|:..|||.||....|.|:||...||:....     |:|.:.
  Fly   131 LLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILG-----TSISVA 190

  Fly   193 --VQIVCSHSWDVQSDFTEEQFQGVLSGVLGSIALL-----LAFLLSI----ESPVDLLEQGNEQ 246
              :.|:....:.::.||.             .|||:     |..||.:    ||...||.:....
  Fly   191 GGITILYGIGYCIRDDFR-------------LIALICCGYQLVALLCVLPLPESHCWLLSKKRVT 242

  Fly   247 GAVQALSRLQRPRAVTAETYDQVRDHRTYVEHH--------RSMGWR--HALPALVRLSVLRALY 301
            .|.::|:..:........|:.||.:....::..        :...||  |.......|.:|.:|:
  Fly   243 EAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLVILMSLF 307

  Fly   302 ALS--LSVMVAFTLAWTSTEVYGDSSGPY---VLFGFLRLMGSFTTSFALDSLGRK---IPLLLG 358
            |..  ..:.|....|...::..|....|:   ||.|..||:.:....:.|:..||:   |...||
  Fly   308 AFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLG 372

  Fly   359 LVISGCLACGLASRFAGSH------------PLTFSGNRMALWLLLIYQLFAGIAFAPSSSYLSE 411
            :.:...|..|        |            |:......:.|..|.:|.|        ....:||
  Fly   373 MSVCMFLLAG--------HSQIEILKEVPYLPVVAIVGFIVLSTLGLYTL--------PFFMISE 421

  Fly   412 AFPRRIKRPCIAITYILEIIVQLLLRQMDFAAIGSDSSYVAL--------------YFFILGGLL 462
            .||::::.|...:|                .|:|...|:|.|              .|.|.|.:.
  Fly   422 LFPQKVRGPASGLT----------------VAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMA 470

  Fly   463 LAGFLFSVWYMPETKDTTLLQAQFKFQ 489
            |...:|....:|||:..|||:.:.:|:
  Fly   471 LFALIFVYLALPETRRRTLLEIEEQFR 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	93/416 (22%)
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	104/480 (22%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	108/485 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740