DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32053 and Tret1-1

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_610693.1	Gene:	Tret1-1 / 36248	FlyBaseID:	FBgn0050035	Length:	857	Species:	Drosophila melanogaster

Alignment Length:	464	Identity:	100/464 - (21%)
Similarity:	185/464 - (39%)	Gaps:	86/464 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 NAVGAAALIFLTGGVHIAWSIGFDSSLSELEVTNHVQICWFIGAII------GALLGGFFSRWFP 115
            :|..:.||:.:|           |.:::..|||.... .| :|.|:      |.:.||....:..
  Fly   414 SAYTSPALVSMT-----------DRNITSFEVTQDAG-SW-VGGIMPLAGLAGGIAGGPLIEYLG 465

  Fly   116 YKTLMEFCSLITITGGIVMAVNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTS 180
            .:..:...::..|...:::|. .:::..:|.||::.|...|:|........||......|||...
  Fly   466 RRNTILATAVPFIVSSLLIAC-AVNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGL 529

  Fly   181 AAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSGVLGSIALLLAFLLSIESPVDLLEQGNE 245
            .    ||..|....::|.    |...|........|...|....|:|.||:. |:|...:.:|.|
  Fly   530 L----PTAFGNIGILLCF----VAGSFMNWSMLAFLGAALPVPFLILMFLIP-ETPRWFVGRGLE 585

  Fly   246 QGAVQALSRLQRPRAVTAETYDQVRD-HRTYVEHHRSMGWRHALPALVRLSVLRALYALSLSVMV 309
            :.|.:||..|   |...|:...:::. .|:..:..|... |:.:..|::|:.|:.| ::||.:|.
  Fly   586 ERARKALKWL---RGKEADVEPELKGLMRSQADADRQAS-RNTMLELLKLNNLKPL-SISLGLMF 645

  Fly   310 --AFT----LAWTSTEVYGDSSGPY------VLFGFLRLMGSFTTSFALDSLGRK-------IPL 355
              .|:    :.:.:.:::.|:....      ::.|.:..:.:|.....:|..|||       |.:
  Fly   646 FQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAM 710

  Fly   356 LLGLVISG----CLACGLASRFAGSHPLTFSGNRMALWLLLIYQLFAGIAFAPSS-SYLSEAFPR 415
            :|.|.:.|    |...|......|..|||         ..:||.|...:.|.|.. ..:.|..|.
  Fly   711 VLTLFVLGGFFYCKTYGPDVSHLGWLPLT---------CFVIYILGFSLGFGPIPWLMMGEILPA 766

  Fly   416 RIKRPCIAI--------TYILEIIVQLLLRQMDFAAIGSDSSYVALYFFILGGLLLAGFLFSVWY 472
            :|:....::        |:::....|.|.     .|:|:..:     |::.|.:...|..|.:.|
  Fly   767 KIRGSAASVATAFNWFCTFVVTKTFQDLT-----VAMGAHGA-----FWLFGAICFVGLFFVIIY 821

  Fly   473 MPETKDTTL 481
            :|||:..||
  Fly   822 VPETQGKTL 830

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	82/393 (21%)
Tret1-1	NP_610693.1	SP	382..833	CDD:273317	100/464 (22%)
Tret1-1	NP_610693.1	MFS	401..822	CDD:119392	94/454 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740