DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32053 and CG32054

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_729588.1	Gene:	CG32054 / 326185	FlyBaseID:	FBgn0052054	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	203/505 - (40%)
Similarity:	306/505 - (60%)	Gaps:	34/505 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PSPDDG----FHVVPIHSDAEQHIHRNSDRQRELILQNSQTSPCCNRDLRNQPQANAVGAAALIF 66
            |.|..|    |:..|......|.....:..|:.:.:.||..|    |:.:|:||:||||||.|||
  Fly    71 PPPQQGYPPQFYGPPPGYGLPQATLPPNPPQQTITVNNSWYS----RNQKNKPQSNAVGAAGLIF 131

  Fly    67 LTGGVHIAWSIGFDSSLSELEVTNHVQICWFIGAIIGALLGGFFSRWFPYKTLMEFCSLITITGG 131
            ::||::|||||||...| ..:.|.|....||||.||||::..|.......|.::.|.|.:.:.||
  Fly   132 VSGGMNIAWSIGFRGVL-HYKTTEHNFAAWFIGGIIGAVISWFLINNVAKKYVLIFSSFLVMIGG 195

  Fly   132 IVMAVNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIV 196
            |:....:...||.||..|::|:||||..||.:|:|||:||.|.||..:::.||....:|||:||:
  Fly   196 ILTTSTKNSGDATLAASYLDGIANGLVFAPFMALAGEVSVSYMRGMVSASIEQMCFGLGIFLQII 260

  Fly   197 CSHSWD-----VQSDFTEEQFQGVLSGVLGSIALLLAFLLSIESPVDLLEQGN-EQGAVQALSRL 255
            .:.:|:     ..:.|:.|..:||||.:.|.:||::..||.|||||.:|.:.| ||||:.||.||
  Fly   261 YTSTWNSTAYPSYNSFSAENMKGVLSIIYGFLALIIGSLLCIESPVIMLAKNNDEQGAIDALRRL 325

  Fly   256 QRPRAVTAETYDQVRDHRTYVEHHR--SMGWR--HALPALVRLSVLRALYALSLS--VMVAFTLA 314
            |||..:|.||::|:.:|:.|:..::  |||..  .|||..:||..||.|.|:|:|  ||:.|..:
  Fly   326 QRPYTLTNETFEQLAEHKKYLAQNKELSMGQSIGQALPTFIRLVFLRGLNAMSISKFVMIGFVYS 390

  Fly   315 WTSTEVY-GDSSGPYVLFGFLRLMGSFTTSFALDSLGRKIPLLLGLVISGCLACGLASRFAGSHP 378
            :.|...| ..|.|.::.||..|.||:|..:|.::|.|||.|.||||::...::..:|.:|   :.
  Fly   391 FASPYGYVSPSVGWFIGFGVCRWMGNFIATFCMESCGRKKPTLLGLIVCSVMSFVVAGQF---NI 452

  Fly   379 LTF-SGNRMALWLLLIYQLFAGIAFAPSSSYLSEAFPRRIKRPCIAITYILEIIVQLLLRQMDFA 442
            .|: :||.:   :||:::|||||||..:|.|||||||..:|:..|:.|:|.|::|.|:|..:.::
  Fly   453 FTYNTGNNI---MLLVFELFAGIAFTATSPYLSEAFPLEVKQHFISFTFIGEMLVFLVLTLIRWS 514

  Fly   443 AIGSDSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTLLQAQFKFQEFV 492
            :.|.     |.||:::|||.|.||.|.:..:|||:.|||.:||.||.:|:
  Fly   515 SSGG-----ANYFYVMGGLYLFGFFFGLVCLPETRRTTLREAQDKFSKFI 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	151/368 (41%)
CG32054	NP_729588.1	Pro-rich	<7..101	CDD:291893	6/29 (21%)
CG32054	NP_729588.1	MFS	157..539	CDD:119392	157/392 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438446
Domainoid	1	1.000	93	1.000	Domainoid score	I13956
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I7306
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005925
OrthoInspector	1	1.000	-	-		mtm9616
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.890