DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32053 and itr1

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_593858.2	Gene:	itr1 / 2543145	PomBaseID:	SPAC4F8.15	Length:	575	Species:	Schizosaccharomyces pombe

Alignment Length:	563	Identity:	122/563 - (21%)
Similarity:	220/563 - (39%)	Gaps:	139/563 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ERPSP------DDGFHVVPIHSDAEQHIHRNSDRQRELILQN-SQTSP-CCNRDLRNQPQANAVG 60
            ::.||      ::...|:|:.|     :.|.|:..|.....| |.:.| ..|..:.:||.:..|.
pombe    29 DKKSPFESSVFENKTQVLPVDS-----VSRLSNGARSRSNSNISLSEPHALNDTVEDQPVSKWVW 88

  Fly    61 AAALIFLTGGVHIAWSIG--------FDSSLSELEVTN----HVQICWFIGAIIGALLGGFFSRW 113
            ..|.....||:...:..|        ..:||...|:||    .:.....:||::|.::.|..:.:
pombe    89 VLAFAAGIGGLLFGYDTGVISGALVVIGTSLGGHELTNGGKEFITSATSLGALLGGIIAGALADF 153

  Fly   114 FPYKTLMEFCSLITITGGIVMAVNRMDLDALLAGRYMNGLANGLA----------IAPTLAMAGE 168
            |..|.::...|:|.|.|.||. |....|..::.||::.|...|:|          |||: .:.|.
pombe   154 FGRKPVIAIASIIIIVGSIVQ-VTAHHLWHMIVGRFVIGWGVGIASLIIPLYLSEIAPS-KIRGR 216

  Fly   169 LSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSG---VLGSIALLLAFL 230
            |.:.|....|....    ...||                 :..|:.|.:|   ::|...:..||.
pombe   217 LVIIYVLLITAGQV----IAYGI-----------------DTAFEHVHNGWRWMVGLAMVPAAFQ 260

  Fly   231 LSI-----ESPVDLLEQGNEQGAVQALSRL---QRPRAVTAETY---DQVRDH----------RT 274
            |.|     |||..|:::...|.|...|:|:   ..|..:..:.|   :.|||.          :|
pombe   261 LFILIWLPESPRLLVKKERSQEAYNTLARIYPTAHPYEIKTKLYLIQEGVRDPFSGSRWQKIVKT 325

  Fly   275 YVE------HHRSMGWRHALPALVRLSVLRALYALSLSVMVAFTLAWTSTEVYG--DSSGPYVLF 331
            :.|      :.|::.....|.|:.:||...:|...|.::.          ||.|  :.:...::.
pombe   326 FKELYFNPSNFRALILACGLQAMQQLSGFNSLMYFSSTIF----------EVVGFNNPTATGLII 380

  Fly   332 GFLRLMGSFTTSFALDSLGRKIPLLLGL--VISGCLACGLASRFAGSHPLTFSGN----RMALWL 390
            .....:.:......:|..||:|.|||.:  :|:..:.|.:|..|.   |...:||    :...|.
pombe   381 AATNFVFTIVAFGVIDFFGRRILLLLTVWGMIAALIVCAVAFHFL---PKDENGNYTSGQSNAWA 442

  Fly   391 LLIYQLFAGIAFAPS-SSYL-------SEAFPRRIKRPCIAITYILEIIVQLLLRQMDFAA-IGS 446
            :::  |.:.|.:..| :|.|       ||.||..::.....::           ..:::|. :|.
pombe   443 IVV--LISMIVYVASYASGLGNLPWQQSELFPMSVRGLGTGMS-----------TAVNWAGNLGI 494

  Fly   447 DSSYVALY--------FFILGGLLLAGFLFSVWYMPETKDTTL 481
            .:|::.|.        |.:.|||...|:|.:::..|:..|.|:
pombe   495 GASFLTLMSEITPTGTFALYGGLCFLGWLGALFCYPDLTDYTI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	91/422 (22%)
itr1	NP_593858.2	Sugar_tr	90..544	CDD:278511	107/497 (22%)
itr1	NP_593858.2	MFS	92..529	CDD:119392	103/485 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900