DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and Slc2a1

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_620182.1	Gene:	Slc2a1 / 24778	RGDID:	3704	Length:	492	Species:	Rattus norvegicus

Alignment Length:	490	Identity:	110/490 - (22%)
Similarity:	193/490 - (39%)	Gaps:	92/490 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 AVGAAALIFL-----TGGVHI-----------AWSIGFDSSLSELEVTN--HVQICWF-IGAIIG 103
            |||.|.|..|     ||.::.           .|:..:..|:....:|.  .:.:..| :|.:||
  Rat    15 AVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWNHRYGESIPSTTLTTLWSLSVAIFSVGGMIG 79

  Fly   104 ALLGGFFSRWFPYKTLMEFCSLITITGGIVMAVNRM--DLDALLAGRYMNGLANGLAIAPTLAMA 166
            :...|.|...|..:..|...:|:.....::|..:::  ..:.|:.||::.|:..||.........
  Rat    80 SFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYV 144

  Fly   167 GELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSGVLGSIALLLAFLL 231
            ||:|....||...:..:     :||.|.|:.:..:.:.|.........:|..|:...|||...||
  Rat   145 GEVSPTALRGALGTLHQ-----LGIVVGILIAQVFGLDSIMGNADLWPLLLSVIFIPALLQCILL 204

  Fly   232 SI--ESPVDLLEQGNEQG-AVQALSRLQRPRAVTAETYDQVRDHR--------TYVEHHRSMGWR 285
            ..  |||..||...||:. |...|.:|:....||.:..:...:.|        |.:|..||..:|
  Rat   205 PFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQMMREKKVTILELFRSPAYR 269

  Fly   286 HALPALV--------RLSVLRALYALSLSVMVAFTLAWTSTEVYGDSSGPYVLFGFLRLMGSFTT 342
            .  |.|:        :||.:.|::..|.|:   |..|.....||.....     |.:....:..:
  Rat   270 Q--PILIAVVLQLSQQLSGINAVFYYSTSI---FEKAGVQQPVYATIGS-----GIVNTAFTVVS 324

  Fly   343 SFALDSLGRKIPLLLGLVISGCLACGLASRFAGSHPLTFSGNRMAL-----WL--LLIYQLFAGI 400
            .|.::..||:...|:||  :|...|.:....|           :||     |:  |.|..:|..:
  Rat   325 LFVVERAGRRTLHLIGL--AGMAGCAVLMTIA-----------LALLEQLPWMSYLSIVAIFGFV 376

  Fly   401 AF-----APSSSYL-SEAFPRRIKRPCIAI----TYILEIIVQLLLRQMDFAAIGSDSSYVALYF 455
            ||     .|...:: :|.|.:..:...:|:    .:....||.:..:.::...    ..||.:.|
  Rat   377 AFFEVGPGPIPWFIVAELFSQGPRPAAVAVAGFSNWTSNFIVGMCFQYVEQLC----GPYVFIIF 437

  Fly   456 FILGGLLLAGFLFSVWYMPETKDTTLLQAQFKFQE 490
            .:   ||:..|:|:.:.:||||..|..:....|::
  Rat   438 TV---LLVLFFIFTYFKVPETKGRTFDEIASGFRQ 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	87/406 (21%)
Slc2a1	NP_620182.1	MFS_GLUT_Class1	14..458	CDD:340989	108/477 (23%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	282..288		2/5 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	468..492		0/2 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337918
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840