back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32053 and SLC2A12

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_660159.1	Gene:	SLC2A12 / 154091	HGNCID:	18067	Length:	617	Species:	Homo sapiens

Alignment Length:	598	Identity:	121/598 - (20%)
Similarity:	205/598 - (34%)	Gaps:	193/598 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 RNQPQANAVGAAALIFLT------GGVHIAWSIGFDS----------SLS----ELEVTNHVQIC 95
            |:.|.|.  |.....||:      .|:.:.:.:|..|          :||    |:.|::.|
Human    28 RHPPWAR--GCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLV--- 87

  Fly    96 WFIGAIIGALLGGFFSRWFPYKTLMEFCSLITITGGIVMAVNRMDLDALLAGRYMNGLANGLAIA 160
              |||::.:|.||.....:..:|.:...|.:...|.:|:.:: :....|:.||...|::..|:..
Human    88 --IGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILS-LSYTVLIVGRIAIGVSISLSSI 149

  Fly   161 PTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIVCS-------HSWDVQSDFTEEQFQGVLS- 217
            .|.....|::..::||...|..|.. ..|||....:.:       |.|       :..|..|:.
Human   150 ATCVYIAEIAPQHRRGLLVSLNELM-IVIGILSAYISNYAFANVFHGW-------KYMFGLVIPL 206

  Fly   218 GVLGSIALLLAFLLSIESPVDLLEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHRSM 282
            |||.:||:.  ||  ..||..|:.:|.|..|.:.|.||   ||::..|.:......:..:.::..
Human   207 GVLQAIAMY--FL--PPSPRFLVMKGQEGAASKVLGRL---RALSDTTEELTVIKSSLKDEYQYS 264

  Fly   283 GWRHALPALVRLSVLRALYALSLSVMVAFTLAWTSTEVYGDSSGPYVLF---------------- 331
            .|          .:.|:...:...:|:..||.: ..::.|.   |.:||
Human   265 FW----------DLFRSKDNMRTRIMIGLTLVF-FVQITGQ---PNILFYASTVLKSVGFQSNEA 315

  Fly   332 --------GFLRLMGSFTTSFALDSLGRKIPLLLG-------LVISGCLACGLASRF---AGSH- 377
                    |.::::.:...:..:|.:|.|..|.:|       ||..|.:...:...|   ..||
Human   316 ASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHN 380

  Fly   378 -------------PLTFSGNRMAL----------------------------------------- 388
                         |...|.|...|
Human   381 SINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHT 445

  Fly   389 ----------------WL----LLIYQLFAGIAFAPSS-SYLSEAFPRRIKRPCIAITYILEIIV 432
                            ||    ||:|.....|...|.. ..|||.||..|:...:|:|..:...:
Human   446 EYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGI 510

  Fly   433 QLLLRQMDFAAIGSDSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTLLQAQFKF--------- 488
            .||: .:.|..: :|...:....||...:.||..||.|.::||||..:|.|...:.
Human   511 NLLI-SLTFLTV-TDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNN 573

  Fly   489 -------QEFVIP 494
                   ||.::|
Human   574 ICFMSHHQEELVP 586

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.