Protein Alignment CG32053 and SLC2A6

DIOPT Version :9

• Sequence 1: NP_729587.1
• Gene: CG32053 / 39178
• FlyBaseID: FBgn0052053
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_060055.2
• Gene: SLC2A6 / 11182
• HGNCID: 11011
• Length: 507
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 119/544 - (21%)
• Similarity: 192/544 - (35%)
• Gaps: 120/544 - (22%)

  Fly     4 ERPSPDDGFHVVPIHSDAEQHIHRNSDRQRELILQNSQTSPCCNRDLRNQPQANAVGAAALIFLT 68
            |:|.|..|                  ||.|...|||.:                 |..|....:.
Human    18 EKPPPSPG------------------DRARVGTLQNKR-----------------VFLATFAAVL 47

  Fly    69 GGVHIAWSIGFDSSL---------SELEVTNHVQICWF-----IGAIIGALLGGFFSRWFPYKTL 119
            |.....:::.:.|.:         .:|.:|.. |..||     :||..|.|.....:.....|..
Human    48 GNFSFGYALVYTSPVIPALERSLDPDLHLTKS-QASWFGSVFTLGAAAGGLSAMILNDLLGRKLS 111

  Fly   120 MEFCSLITITGGIVMAVNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAAEQ 184
            :.|.::.:..|..:|| ....|..||.||.:.|.|.||..|.......|::....||    |...
Human   112 IMFSAVPSAAGYALMA-GAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRG----ALGA 171

  Fly   185 WPTTIGIF-------VQIVCSHSWDVQSDFTEEQFQGVLSGVLGSI-ALLLAFLLSI--ESPVDL 239
            .|..:.:|       :.::....|               ..|.|.. .|::..|||.  .||..|
Human   172 TPQLMAVFGSLSLYALGLLLPWRW---------------LAVAGEAPVLIMILLLSFMPNSPRFL 221

  Fly   240 LEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHRS-MGWRHA------LPALVRLSVL 297
            |.:|.::.|::||:.|:.........::|::|:   |....| :.|..|      .|..|.| ::
Human   222 LSRGRDEEALRALAWLRGTDVDVHWEFEQIQDN---VRRQSSRVSWAEARAPHVCRPITVAL-LM 282

  Fly   298 RALYALS--LSVMVAFTLAWTSTEVYGDSSGPYVLFGFLRLMGSFTTSFALDSLGRKI------- 353
            |.|..|:  ..::|.....:.||.|.........:.|.:||:.....:..:|..|||:
Human   283 RLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAA 347

  Fly   354 -----PLLLGLVI-------SGCLACGLASRFAG--SHPLTFSGNRMALWLLLIYQLFA---GIA 401
                 .|.|||.|       |.....||.|...|  :.||......:.|..||...||.   .:.
Human   348 IMFAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVG 412

  Fly   402 FAPSSSYL-SEAFPRRIKRPCIAITYILEIIVQLLLRQMDFAAIGSDSSYVALYFFILGGLLLAG 465
            :.|.:..| ||..|.|.:.....:..:...:...:|.:.....:.:....|..:||  ..:.|..
Human   413 WGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFF--AAICLVS 475

  Fly   466 FLFSVWYMPETKDTTLLQAQFKFQ 489
            .:|:...:||||..:|.|.:..|:
Human   476 LVFTGCCVPETKGRSLEQIESFFR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	93/412 (23%)
SLC2A6	NP_060055.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		5/27 (19%)
		Dileucine internalization motif. /evidence=ECO:0000255	5..6
		MFS_GLUT6_Class3	39..493	CDD:340992	106/480 (22%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	286..292		1/5 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144234
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740